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Phenyl vinyl sulfone

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Phenyl vinyl sulfone Basic information

Product Name:
Phenyl vinyl sulfone
Synonyms:
  • VINYL PHENYL SULFONE
  • Eletriptan intermediate 1
  • Phenylvinylsulfone,99+%
  • Benzene, (ethenylsulfonyl)-
  • 1,1'-Sulfonylbis(ethene-1,1-diyl)dibenzene
  • Phenyl vinyl sulphone, 99+%
  • 1-(Phenylsulfonyl)ethene
  • (ethenesulfonyl)benzene
CAS:
5535-48-8
MF:
C8H8O2S
MW:
168.21
EINECS:
226-890-2
Product Categories:
  • Bioactive Small Molecules
  • Building Blocks
  • Cell Biology
  • Chemical Synthesis
  • Organic Building Blocks
  • P
  • Pharmaceutical material and intermeidates
  • Sulfur Compounds (for Synthesis)
  • Synthetic Organic Chemistry
  • Naphthyridine,Quinoline
  • Organic Building Blocks
  • Sulfones
  • Sulfur Compounds
  • Sulfur Compounds
Mol File:
5535-48-8.mol
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Phenyl vinyl sulfone Chemical Properties

Melting point:
67-69 °C (lit.)
Boiling point:
267.16°C (rough estimate)
Density 
1.2660 (rough estimate)
refractive index 
1.5090 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
It is soluble in most common organic solvents.
form 
Solid
color 
White
BRN 
1906894
Stability:
Stable. Incompatible with strong oxidizing agents.
InChIKey
UJTPZISIAWDGFF-UHFFFAOYSA-N
CAS DataBase Reference
5535-48-8(CAS DataBase Reference)
NIST Chemistry Reference
Benzene, (ethenylsulfonyl)-(5535-48-8)
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Safety Information

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-43-41-37/38-22
Safety Statements 
26-36/37/39-37/39
WGK Germany 
3
HS Code 
29309090

MSDS

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Phenyl vinyl sulfone Usage And Synthesis

Chemical Properties

off-white or tan powder

Uses

Phenyl Vinyl Sulfone is a synthetic inhibitor of cysteine protease and has antihelminthic and antiprotozoal properties. Phenyl Vinyl Sulfone is also an inhibitor of transpeptidase SrtA required for cell wall protein anchoring and virulence in Staphylococcus aureus.

Uses

As common reagent, Phenyl vinyl sulfone is used in a variety of cycloaddition reactions to form cyclopropanes,1 cyclohexenes,2,3 and cyclooctadienes.

Synthesis Reference(s)

The Journal of Organic Chemistry, 48, p. 4976, 1983 DOI: 10.1021/jo00173a039

General Description

Phenyl vinyl sulfone, a synthetic inhibitor of cysteine protease, exhibits antihelminthic and antiprotozoal properties.

Phenyl vinyl sulfone Preparation Products And Raw materials

Raw materials

Phenyl vinyl sulfoneSupplier

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