Basic information Safety Supplier Related

ACETYLCHOLINE BROMIDE

Basic information Safety Supplier Related

ACETYLCHOLINE BROMIDE Basic information

Product Name:
ACETYLCHOLINE BROMIDE
Synonyms:
  • Acetylcholine bromide;2-(Acetyloxy)-N,N,N-trimethylethanaminium bromide
  • PRAGMOLINE
  • N-(2-HYDROXYETHYL)TRIMETHYLAMMONIUM BROMIDE ACETATE
  • 2-ACETOXYETHYLTRIMETHYLAMMONIUM BROMIDE
  • ACH
  • ACETYLCHOLINE BROMIDE
  • (2-Hydroxyethyl)trimethylammoniumbromideacetate
  • 2-(acetyloxy)-n,n,n-trimethyl-ethanaminiubromide
CAS:
66-23-9
MF:
C7H16BrNO2
MW:
226.11
EINECS:
200-622-4
Product Categories:
  • Ammonium Bromides (Quaternary)
  • Quaternary Ammonium Compounds
Mol File:
66-23-9.mol
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ACETYLCHOLINE BROMIDE Chemical Properties

Melting point:
140-143 °C(lit.)
Density 
1.4246 (rough estimate)
refractive index 
1.6120 (estimate)
storage temp. 
-20°C
solubility 
Methanol (Slightly), Water (Slightly)
form 
Solid
color 
Off-White
Water Solubility 
almost transparency
Sensitive 
Hygroscopic
Merck 
14,86
BRN 
3572117
CAS DataBase Reference
66-23-9(CAS DataBase Reference)
EPA Substance Registry System
Acetylcholine bromide (66-23-9)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39
WGK Germany 
3
RTECS 
FZ9680000
3-8-10-23
HS Code 
29379000

MSDS

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ACETYLCHOLINE BROMIDE Usage And Synthesis

Chemical Properties

WHITE TO LIGHT BEIGE ADHERING CRYSTALLINE SOLID

Uses

Acetylcholine is an endogenous neurotransmitter at cholinergic synapses that amplifies action potential of the sarcolemma thereby inducing muscle contractions. Acetylcholine bromide is used as an acetylcholine receptor agonist to identify, characterize and differentiate among types of cholinergic receptors. Acetylcholine bromide is used as an inhibitor to identify and characterize natural and mutated butyrylcholinesterase(s).

Definition

ChEBI: The bromide salt of acetylcholine.

Biochem/physiol Actions

Endogenous neurotransmitter at cholinergic synapses; amplifies action potential of the sarcolemma thereby inducing muscle contractions.

Purification Methods

The bromide is a hygroscopic solid, but less so than the hydrochloride salt. It crystallises from EtOH as prisms. Some hydrolysis occurs in boiling EtOH, particularly if it contains some H2O. It can also be recrystallised from EtOH or MeOH by adding dry Et2O. [Heilbronn Acta Chem Scand 12 1492 1958, Beilstein 4 IV 1446.]

ACETYLCHOLINE BROMIDE Preparation Products And Raw materials

Raw materials

ACETYLCHOLINE BROMIDESupplier

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