Basic information Safety Supplier Related

4-[(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINEETHANOL DIHYDROCHLORIDE

Basic information Safety Supplier Related

4-[(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINEETHANOL DIHYDROCHLORIDE Basic information

Product Name:
4-[(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINEETHANOL DIHYDROCHLORIDE
Synonyms:
  • 2-{4-[(4-CHLORO-PHENYL)-PHENYL-METHYL]-PIPERAZIN-1-YL}-ETHANOL
  • 2-[4-{Chlorophenyl}Phenylmethyl]-1-
  • 2-[4-{4-Chlorophenyl} Phenylmethyl]-1-Piperazinylethanol
  • Levocetirizine Impurity G
  • 4-[(4-Chlorophenyl)phenylMethyl]-(4-hydroxy-1-piperidinyl)-1-butanone
  • 1-Piperazineethanol, 4-[(4- chlorophenyl)phenylMethyl]-
  • (R)-2-(4-((4-chlorophenyl)
  • Levocetirizine Impurity 6
CAS:
109806-71-5
MF:
C19H23ClN2O
MW:
330.85
Product Categories:
  • (intermediate of cetirizine dihydrochloride)
Mol File:
109806-71-5.mol
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4-[(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINEETHANOL DIHYDROCHLORIDE Chemical Properties

Boiling point:
205-208 °C(Press: 0.1 Torr)
Density 
1.191±0.06 g/cm3(Predicted)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
Ethyl Acetate (Slightly), Methanol (Slightly)
form 
Solid
pka
14.96±0.10(Predicted)
color 
White to Off-White
Stability:
Very Hygroscopic
CAS DataBase Reference
109806-71-5(CAS DataBase Reference)
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4-[(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINEETHANOL DIHYDROCHLORIDE Usage And Synthesis

Chemical Properties

Off-White Solid

Uses

4-(p-Chloro-α-phenylbenzyl)-1-piperazineethanol is used in the synthesis of antifungal triazole and imidazole derivatives. Impurity of an intermediate in the formation of Cetrizine.

Uses

2-[4-[(4-Chlorophenyl)phenylmethyl]-1-piperazinyl]ethanol is an impurity of (R)-Cetirizine (C281106).

4-[(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINEETHANOL DIHYDROCHLORIDE Preparation Products And Raw materials

Raw materials

4-[(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINEETHANOL DIHYDROCHLORIDESupplier

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