(2-{[2-(2-fluorophenoxy)ethyl]sulfanyl}-1H-benzimidazol-1-yl)acetic acid Chemical Properties

form 

Solid

color 

White to off-white

(2-{[2-(2-fluorophenoxy)ethyl]sulfanyl}-1H-benzimidazol-1-yl)acetic acid Usage And Synthesis

Uses

PDK1 allosteric modulator 1 is a molecule targeting PDK1 with a binding affinity of 8 μM. PDK1 allosteric modulator 1 is able to bind to the PIF pocket of PDK1, potentially affecting the biological activity of this kinase[1].

References

[1] Small-Molecule Allosteric Modulators of the Protein Kinase PDK1 from Structure-Based Docking

(2-{[2-(2-fluorophenoxy)ethyl]sulfanyl}-1H-benzimidazol-1-yl)acetic acid(303134-93-2)Related Product Information

• 2-Furancarboxamide, N-(2-chlorophenyl)-5-[(2-methoxyphenoxy)methyl]-
• 2-Furancarboxamide, 5-[[4-(1,1-dimethylethyl)phenoxy]methyl]-N-(2-methoxyphenyl)-
• Acetic acid, 2-[(5E)-5-[(5-methyl-2-thienyl)methylene]-4-oxo-2-thiazolidinylidene]-, ethyl ester, (2E)-
• Benzamide, N-[(3-chlorophenyl)methyl]-3-[(hexahydro-1H-azepin-1-yl)sulfonyl]-
• Propanoic acid, 2-[(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)thio]-
• WAY-640509
• N-benzyl-2-[4-[(E)-3-phenylprop-2-enyl]piperazin-1-yl]acetamide
• Thiourea, N-(2-fluorophenyl)-N'-[1-(phenylmethyl)-4-piperidinyl]-
• WAY 361789
• 2-(4-chloro-2-methylphenoxy)-N-(4,5-dihydro-1,3-thiazol-2-yl)acetamide
• 1H-Isoindole-1,3(2H)-dione, 2-[3-[4-(2-hydroxyethyl)-1-piperazinyl]-3-oxopropyl]-
• Benzo[b]thiophene-2-carboxamide, 5-fluoro-N-[3-(4-morpholinylsulfonyl)phenyl]-
• 5H-Cyclopenta[4,5]thieno[2,3-d]pyrimidine, 6,7-dihydro-4-(1-piperidinyl)-
• 4-Piperidinecarboxamide, 1-[3-(3,4-dihydro-4-oxo-2-quinazolinyl)-1-oxopropyl]-
• WAY-600
• 5-bromo-N-(2-morpholin-4-ylethyl)pyridine-3-carboxamide
• Glycinamide, N-acetylglycyl-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-N2-methyl-2-phenyl- (9CI)
• Benzamide, 4-(3,5-dimethyl-1H-pyrazol-1-yl)-N-(4-methyl-2-thiazolyl)-