Propanoic acid, 2-[(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)thio]- Chemical Properties

Melting point:

208-209 °C

Boiling point:

473.2±45.0 °C(Predicted)

Density 

1.41±0.1 g/cm3(Predicted)

pka

3.09±0.10(Predicted)

Propanoic acid, 2-[(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)thio]- Usage And Synthesis

Uses

CK2-IN-8 (compound 5c) is a CK2 inhibitor with IC50 >33 μM[1].

References

[1] Golub AG, et al. Synthesis and biological evaluation of substituted (thieno[2,3-d]pyrimidin-4-ylthio)carboxylic acids as inhibitors of human protein kinase CK2. Eur J Med Chem. 2011 Mar;46(3):870-6. DOI:10.1016/j.ejmech.2010.12.025

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