Basic information Safety Supplier Related

GAMABUFOTALIN

Basic information Safety Supplier Related

GAMABUFOTALIN Basic information

Product Name:
GAMABUFOTALIN
Synonyms:
  • GAMABUFOTALIN
  • 22-dienolide,3,11,14-trihydroxy-,(3-beta,5-beta,11-alpha)-bufa-2
  • 22-dienolide,3-beta,11-alpha,14-trihydroxy-5-beta-bufa-2
  • 3,11,14-Trihydroxybufa-20,22-dienolide
  • 3-beta,11-alpha,14-Trihydroxy-5-beta-bufa-20,22-dienolide
  • 5beta-Bufa-20,22-dienolide, 3beta,11alpha,14-trihydroxy-
  • Bufa-20,22-dienolide, 3,11,14-trihydroxy-, (3beta,5beta,11alpha)-
  • Gamabufotalin (Gamabufagin)
CAS:
465-11-2
MF:
C24H34O5
MW:
402.52
Mol File:
465-11-2.mol
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GAMABUFOTALIN Chemical Properties

Melting point:
254°
alpha 
D18 +1.26° (c = 0.793 in methanol)
Boiling point:
595.8±50.0 °C(Predicted)
Density 
1.289±0.06 g/cm3(Predicted)
pka
14.52±0.70(Predicted)
form 
Solid
color 
White to off-white
optical activity
-13±219 (c 0.931, methanol)
CAS DataBase Reference
465-11-2
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GAMABUFOTALIN Usage And Synthesis

Description

Gamabufotalin belongs to the bufastenolide compound contained in traditional Chinese medicine toadstool. Previous studies have shown that CS-6 has a good effect in inhibiting tumor cell growth and inflammatory response.

Chemical Properties

White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from toad secretions.

Uses

Gamabufotalin has a strong heart and anti-tumor effect.

Definition

ChEBI: Gamabufogenin is a steroid lactone. It is functionally related to a bufanolide.

Biological Activity

Gamabufotalin (Gamabufagin), the main bufastenene in Bufonis bufa, is widely used in cancer research due to its stability and low toxicity.

GAMABUFOTALINSupplier

Chembest Research Laboratories Limited
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Chengdu Biopurify Phytochemicals Ltd.
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Chengdu Climax Biotech Co., Ltd.
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