ChemicalBook > Product Catalog > Chemical Reagents > Organic reagents > Esters > Other esters > Bufotaline
Bufotaline
Bufotaline Basic information
- Product Name:
- Bufotaline
- Synonyms:
-
- 3-BETA-14,16-BETA-TRIHYDROXY-5BETA-BUFA-20,22-DIENOLIDE SULFATE
- 16-(Acetyloxy)-3,14-dihydroxybufa-20,22-dienolide
- 22-dienolide,3-beta,14,16-beta-trihydroxy-5-beta-bufa-216-acetate
- 5beta-Bufa-20,22-dienolide, 3beta,14,16beta-trihydroxy-, 16-acetate
- Bufa-20,22-dienolide, 16-(acetyloxy)-3,14-dihydroxy-, (3beta,5beta,16beta)-
- Bufotaline
- BUFOTALIN
- BUFOTALIN SULFATE
- CAS:
- 471-95-4
- MF:
- C26H36O6
- MW:
- 444.56
- Product Categories:
-
- Miscellaneous Natural Products
- Mol File:
- 471-95-4.mol
More
Less
Bufotaline Chemical Properties
- Melting point:
- 223°C (rough estimate)
- Boiling point:
- 474.53°C (rough estimate)
- alpha
- D20 +5.4° (c = 0.5 in chloroform)
- Density
- 1.0942 (rough estimate)
- refractive index
- 1.4593 (estimate)
- storage temp.
- Store at -20°C
- solubility
- DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml
- form
- White to off-white solid.
- pka
- 14.44±0.70(Predicted)
- color
- White to off-white
- CAS DataBase Reference
- 471-95-4
- NIST Chemistry Reference
- Bufotalin(471-95-4)
More
Less
Bufotaline Usage And Synthesis
Chemical Properties
Crystalline genin.
Uses
Bufotalin is a component of Bufo bufo gargarizans which acts as an anti-tumor agent.
Definition
ChEBI: Bufotalin is a steroid lactone. It is functionally related to a bufanolide.
Hazard
Deadly poison.
in vivo
Bufotalin (0.5-1 mg/kg; intraperitoneal injection; twice daily; for 7 days) treatment shows a significantly reduced tumor growth in mice[1].
| Animal Model: | SCID male mice (4-6 weeks old) injected with U2OS cells[1] |
| Dosage: | 0.5 mg/kg, 1 mg/kg |
| Administration: | Intraperitoneal injection; twice daily; for 7 days |
| Result: | Inhibited U2OS osteoblastoma cell growth in mice. |
BufotalineSupplier
Chembest Research Laboratories Limited
- Tel
- +86-21-20908456
- sales@BioChemBest.com
Nanjing Chemlin Chemical Co., Ltd
- Tel
- 025-83697070
- info@chemlin.com.cn
BOC Sciences
- Tel
- 1-631-485-4226; 16314854226
- info@bocsci.com
Dalian Meilun Biotech Co., Ltd.
- Tel
- 0411-62910999 13889544652
- sales@meilune.com
BioBioPha Co., Ltd.
- Tel
- 0871-65217109 13211707573;
- y.liu@mail.biobiopha.com