4-Iodobenzylamine hydrochloride Chemical Properties

Melting point:

299-303 °C(lit.)

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

Appearance

White to off-white Powder

Water Solubility 

Soluble in water.

Sensitive 

Light Sensitive

BRN 

3691299

InChI

1S/C7H8IN.ClH/c8-7-3-1-6(5-9)2-4-7;/h1-4H,5,9H2;1H

InChIKey

GBJMURRFWZREHE-UHFFFAOYSA-N

SMILES

Cl[H].NCc1ccc(I)cc1

CAS DataBase Reference

59528-27-7(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

22-24/25-37-26

WGK Germany 

3

Hazard Note 

Irritant/Light Sensitive

HS Code 

29214990

Storage Class

11 - Combustible Solids

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

4-Iodobenzylamine hydrochloride Usage And Synthesis

Uses

4-Iodobenzylamine hydrochloride is used to prepare cyclic amide by reacting with methyl 4-bromomethyl-3-methoxycarbonylcinnamate in the presence of triethylamine. It is also used in pharmaceuticals, agrochemicals and dye industries.

General Description

4-Iodobenzylamine hydrochloride can be synthesized in three steps from 4-iodobenzoic acid.

Synthesis

To a suspension of 4-iodobenzamide (11 g, 45 mmol) in THF (50 mL) was added BH3-THF (1M, 22.5 mL, ). 22.5 mmol). The resulting solution was heated to reflux overnight. The reaction was cooled in an ice bath and MeOH-HCl (60 mL) was added slowly and dropwise. The resulting precipitate was filtered and dried to give 4-iodobenzylamine hydrochloride. White solid, yield 10.8 g, 88%.

4-Iodobenzylamine hydrochloride(59528-27-7)Related Product Information

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• 3-IODOBENZYLAMINE HYDROCHLORIDE,M-IODOBENZYLAMINE HYDROCHLORIDE
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