Basic information Methoxyamine hydrochloride Application Safety Supplier Related
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Methoxyammonium chloride

Basic information Methoxyamine hydrochloride Application Safety Supplier Related

Methoxyammonium chloride Basic information

Product Name:
Methoxyammonium chloride
Synonyms:
  • Methoxyamine Hydrochloride, O-Methylhydroxylamine hydrochloride, Methoxylamine hydrochloride
  • Methoxylamine hydrochloride solution 25-30 wt. % in H2O
  • Hydroxylamine, O-methyl-, hydrochloride (1:1)
  • O-METHYLHYDROXYAMINE HYDROCHLORIDE
  • O-METHYLHYDROXYLAMINE HCL
  • O-METHYLHYDROXYLAMINE HYDROCHLORIDE
  • O-METHYLHYDROXYLAMMONIUM CHLORIDE
  • MOX REAGENT
CAS:
593-56-6
MF:
CH6ClNO
MW:
83.52
EINECS:
209-798-7
Product Categories:
  • Amine Salts
  • Amino Alcohols
  • Building Blocks
  • Chemical Synthesis
  • Nitrogen Compounds
  • Organic Building Blocks
  • Amines and Anilines
  • API intermediates
  • Amination
  • Hydroxylamines
  • Hydroxylamines (O-Substituted)
  • Synthetic Organic Chemistry
  • Oxygen Compounds
Mol File:
593-56-6.mol
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Methoxyammonium chloride Chemical Properties

Melting point:
151-154 °C(lit.)
Boiling point:
105-110°C
Density 
1.1 g/mL at 25 °C
refractive index 
n20/D 1.4021
storage temp. 
Sealed in dry,Room Temperature
solubility 
alcohol: soluble(lit.)
form 
Crystalline Powder
color 
White to very faint yellow
Water Solubility 
SOLUBLE
Sensitive 
Hygroscopic
Merck 
14,5989
BRN 
3589723
InChIKey
XNXVOSBNFZWHBV-UHFFFAOYSA-N
CAS DataBase Reference
593-56-6(CAS DataBase Reference)
EPA Substance Registry System
O-Methylhydroxylamine hydrochloride (593-56-6)
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Safety Information

Hazard Codes 
C,Xi,N
Risk Statements 
34-36/37/38-50-43-20/21/22-37-35
Safety Statements 
3-24-26-36/37/39-45-61-24/25-27
RIDADR 
UN 3265 8/PG 2
WGK Germany 
3
RTECS 
NC3980000
3-10
Hazard Note 
Corrosive/Hygroscopic
TSCA 
Yes
HS Code 
2928 00 90
HazardClass 
8
PackingGroup 
III

MSDS

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Methoxyammonium chloride Usage And Synthesis

Methoxyamine hydrochloride

Methoxyamine hydrochloride (also known as O-methylhydroxylamine hydrochloride; Methoxyamine; Methoxyamine hydrochloride (OMHA), is an important medicine, pesticide intermediates. Its major applications are as follows:

  • it can be used for color photography and film printing.
  • it is used as a reducing agent in organic synthesis industry for preparation of oximes.
  • the field of medicine: it can be used for the synthesis of second-generation cephalosporins antibiotics cefuroxime (ester), neopropene, norethindine and hydroxyurea.
  • the field of pesticides: the synthesis of new efficient, low-toxicity bactericidal metominostrobin.
  • It is mainly produced by sodium nitrite method in our country.
The similar compound of methoxyamine hydrochloride, the ethoxylamine hydrochloride is mainly used for the production of herbicides, oxycarbazone, diltiazem and other herbicides.

Application

  • Used as a methoxyamine reagent, also used in the production of the side chain of Cefuroxime and other new drugs
  • Used for pesticide synthesis.
  • Use for pharmaceuticals production
  • Used for the preparation of O-methyloxime together with aldehydes or ketones.

Chemical Properties

White to very faintly yellow crystalline powder

Uses

antineoplastic, hydroxymethyltransferase inhibitor

Uses

Methoxylamine is a methoxime derivative used as internal standard for Prostaglandin assays by gas chromatography-mass spectrometry

Uses

Methoxylamine hydrochloride is used as a reagent in the preparation of O-methyl oximes from aldehydes. It is orally bioavailable small molecule inhibitor with potential adjuvant activity. It is also used as internal standard for prostaglandin assays by gas chromatography-mass spectrometry.

General Description

Off-white crystals.

Air & Water Reactions

Water soluble.

Reactivity Profile

In aqueous solution, Methoxyammonium chloride behaves as an acid. Materials in this group are generally soluble in water. The resulting solutions contain moderate concentrations of hydrogen ions and have pH's of less than 7.0. They react as acids to neutralize bases. These neutralizations generate heat, but less or far less than is generated by neutralization of inorganic acids, inorganic oxoacids, and carboxylic acid. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible. Many of these compounds catalyze organic reactions.

Fire Hazard

Flash point data for Methoxyammonium chloride are not available. Methoxyammonium chloride is probably combustible.

Purification Methods

Crystallise the hydrochloride from absolute EtOH or EtOH by addition of diethyl ether. [Kovach et al. J Am Chem Soc 107 7360 1985, Beilstein 1 IV 1252.]

Methoxyammonium chloride Preparation Products And Raw materials

Preparation Products

Methoxyammonium chlorideSupplier

Taizhou Huaxi Technology Co. LTD Gold
Tel
0576-89164227- ;
Email
18323010@qq.com;97621963@qq.com
Products Intro
Product Name:O-METHYLHYDROXYLAMINE HCL
CAS:593-56-6
Purity:含量≥98% Package:2300
Meryer (Shanghai) Chemical Technology Co., Ltd. Gold
Tel
+86-021-61259100
Email
int02@meryer.com
Products Intro
Product Name:MethoxylaMine hydrochloride
CAS:593-56-6
Purity:99% Package:25g;100g Remarks:AAA123611
Ningbo Ocean Chemical New Materials Technology Co., Ltd. Gold
Tel
0574-86508062
Email
sales@nboceanchem.com
Products Intro
Product Name:Methoxylamine Hydrochloride; O-Methylhydroxylamine Hydrochloride
CAS:593-56-6
Purity:98.5% GC Package:25KG;500KG
Tianjin Hexin Chengsai Science and Technology Development Co., Ltd. Gold
Tel
022-23410962-
Email
suna@hisyntech.com
Products Intro
CAS:593-56-6
Purity:98.5%
Beijing OKA biological technology co., LTD Gold
Tel
010-62971590-
Email
3462612863@qq.com
Products Intro
Product Name:Methoxyamine hydrochloride
CAS:593-56-6
Purity:98% Package:500g;100g