Basic information Safety Supplier Related

S(-)-VERAPAMIL

Basic information Safety Supplier Related

S(-)-VERAPAMIL Basic information

Product Name:
S(-)-VERAPAMIL
Synonyms:
  • S(-)-VERAPAMIL
  • S(-)-VERAPAMIL HYDROCHLORIDE
  • S-Verapamil HCL
  • [7-cyano-1,7-bis(3,4-dimethoxyphenyl)nonan-3-yl]ammonium chloride
  • (-)-[3-cyano-3-(3,4-dimethoxyphenyl)hex-6-yl][2-(3,4-dimethoxyphenyl)ethyl]methylammonium chloride
  • S(-)-VERAPAMIL HYDROCHLORIDE HYDRATE
  • Benzeneacetonitrile, a-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-a-(1-methylethyl)-, monohydrochloride, (aS)- (9CI)
  • Benzeneacetonitrile, a-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-a-(1-methylethyl)-, monohydrochloride, (S)-
CAS:
36622-28-3
MF:
C27H38N2O4
MW:
454.6
EINECS:
253-132-8
Product Categories:
  • Calcium Channel Modulators
  • Verapamil
  • Organics
  • Voltage-gated Ion Channels
Mol File:
36622-28-3.mol
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S(-)-VERAPAMIL Chemical Properties

Melting point:
131-133 °C
solubility 
H2O: >30 mg/mL
form 
solid
color 
white
optical activity
[α]22/D 6.1°, c = 0.1 in ethanol(lit.)
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Safety Information

Hazard Codes 
T
Risk Statements 
25
Safety Statements 
45
RIDADR 
UN 2811 6.1/PG 3
WGK Germany 
3
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S(-)-VERAPAMIL Usage And Synthesis

Chemical Properties

White Solid

Uses

Both isomers inhibit the p-glycoprotein efflux pump in multidrug resistant tumor cells.

Definition

ChEBI: (S)-verapamil hydrochloride is a hydrochloride salt resulting from the reaction of equimolar amounts of (S)-verapamil and hydrogen chloride. It is an enantiomer of a dexverapamil hydrochloride.

Biochem/physiol Actions

Active enantiomer of (±)-verapamil. Ca2+ channel (L-type) modulator; adrenoceptor antagonist; cardiac depressant.

S(-)-VERAPAMILSupplier

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