8-BROMOADENOSINE 3':5'-CYCLIC MONOPHOSPHATE Chemical Properties

Melting point:

254 °C (dec.) (lit.)

Boiling point:

741.9±70.0 °C(Predicted)

Density 

2.80±0.1 g/cm3(Predicted)

storage temp. 

-20°C

solubility 

aqueous base: soluble

pka

0.95±0.60(Predicted)

form 

Powder

color 

Pale Brown

Sensitive 

Hygroscopic

BRN 

591930

Safety Information

Safety Statements 

22-24/25

WGK Germany 

3

F 

3-10

HS Code 

29349990

MSDS

• Language:English Provider:SigmaAldrich

8-BROMOADENOSINE 3':5'-CYCLIC MONOPHOSPHATE Usage And Synthesis

Chemical Properties

White powder

Uses

8-Bromoadenosine 3′,5′-cyclic monophosphate has been used:

• to treat H295R cells as positive controls for CYP19 induction
• as a membrane permeable cAMP analog to study its effect on short-circuit current (I_sc)
• to investigate its potential as an inducer of differentiation in Wharton′s jelly-derived mesenchymal stem cells (WJ-MSCs)

Definition

ChEBI: A 3',5'-cyclic purine nucleotide that is 3',5'-cyclic AMP bearing an additional bromo substituent at position 8 on the adenine ring. An activator of cyclic AMP-dependent protein kinase.

Biochem/physiol Actions

8-bromo-adenosine?3′,5′-cyclic?monophosphate?(8-bromo-cAMP), added to hepatocytes during plating helps to increase the acquisition of beta-adrenoceptors.

8-BROMOADENOSINE 3':5'-CYCLIC MONOPHOSPHATE(23583-48-4)Related Product Information

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