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8-BROMOADENOSINE

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8-BROMOADENOSINE Basic information

Product Name:
8-BROMOADENOSINE
Synonyms:
  • 8-BROMOADENINE-9-BETA-D-RIBOFURANOSIDE
  • 8-BROMOADENOSINE
  • 6-AMINO-8-BROMOPURINE RIBOSIDE
  • (2R,3R,4S,5R)-2-(6-AMINO-8-BROMO-PURIN-9-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL
  • 8-BROMOADENOSINE, HPLC PURIFIED, 98% PURE WITH HPLC UV CHROMATOGRAM
  • 8-BROMO-D-ADENOSINE
  • 6-Amino-8-bromopurine riboside, 8-Bromoadenine-9-β-D-ribofuranoside
  • 8-Bromoadenosine,98%
CAS:
2946-39-6
MF:
C10H12BrN5O4
MW:
346.14
EINECS:
220-959-0
Product Categories:
  • Pyridines, Pyrimidines, Purines and Pteredines
  • Nucleotides and Nucleosides
  • Bases & Related Reagents
  • Nucleotides
Mol File:
2946-39-6.mol
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8-BROMOADENOSINE Chemical Properties

Melting point:
210-212 °C (dec.)(lit.)
Boiling point:
717.7±70.0 °C(Predicted)
Density 
1.8171 (rough estimate)
refractive index 
1.6400 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility 
DMSO (Slightly), Methanol (Slightly, Sonicated)
pka
12.89±0.70(Predicted)
form 
powder
color 
white
Water Solubility 
Soluble in DMSO, and DMF. Insoluble in water.
Sensitive 
Air Sensitive
BRN 
627737
CAS DataBase Reference
2946-39-6(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-24/25-22
WGK Germany 
3
10-23
HS Code 
2934 99 90

MSDS

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8-BROMOADENOSINE Usage And Synthesis

Description

8-Bromoadenosine is a nucleotide that is structurally related to adenosine. It can be used as an inhibitor of guanine nucleotide-binding proteins and has shown biological properties in vitro. 8-Bromoadenosine has been shown to inhibit the mitochondrial membrane potential, cytosolic Ca2+, and the synthesis of RNA and protein. 8-Bromoadenosine also inhibits leukemia inhibitory factor (LIF) production by 3T3-L1 preadipocytes and induces apoptosis in T84 cells.

Chemical Properties

Off-White Solid

Uses

8-Bromoadenosine is an adenosine binding inhibitor. formation of 8-S-L-cysteinyladenosine from 8-Bromoadenosine and cysteine.

Definition

ChEBI: 8-Bromoadenosine is a purine nucleoside.

8-BROMOADENOSINESupplier

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