Basic information Safety Supplier Related

16α-Hydroxy-24-methylene-3-oxo-5α-lanosta-7,9(11)-diene-21-oic acid

Basic information Safety Supplier Related

16α-Hydroxy-24-methylene-3-oxo-5α-lanosta-7,9(11)-diene-21-oic acid Basic information

Product Name:
16α-Hydroxy-24-methylene-3-oxo-5α-lanosta-7,9(11)-diene-21-oic acid
Synonyms:
  • 16α-Hydroxy-24-methylene-3-oxo-5α-lanosta-7,9(11)-dien-21-oic acid
  • 16α-Hydroxy-24-methylene-3-oxo-5α-lanosta-7,9(11)-diene-21-oic acid
  • 3-Oxo-16α-hydroxy-24-methylene-5α-lanosta-7,9(11)-diene-21-oic acid
  • Polyporenic acid C
  • 16alpha-Hydroxy-24-methylene-3-oxo-5alpha-lanosta-7,9(11)-diene-30-oic acid
  • Lanosta-7,9(11)-dien-21-oic acid, 16-hydroxy-24-methylene-3-oxo-, (16α)-
  • (2S)-2-[(10S,13R,14R,16R,17R)-16-hydroxy-4,4,10,13,14-pentamethyl-3-oxo-1,2,5,6,12,15,16,17-octahydrocyclopenta[a]phenanthren-17-yl]-6-methyl-5-methylideneheptanoic acid
  • cell,Apoptosis,inhibit,Inhibitor,lung,cancer,NSCLC,Polyporenic acid C
CAS:
465-18-9
MF:
C31H46O4
MW:
482.69
Product Categories:
  • Triterpenoids
Mol File:
465-18-9.mol
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16α-Hydroxy-24-methylene-3-oxo-5α-lanosta-7,9(11)-diene-21-oic acid Chemical Properties

Melting point:
265-266℃
Boiling point:
620.3±55.0 °C(Predicted)
Density 
1.11±0.1 g/cm3(Predicted)
storage temp. 
4°C, protect from light
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
Powder
pka
4.63±0.10(Predicted)
color 
White to off-white
CAS DataBase Reference
465-18-9
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16α-Hydroxy-24-methylene-3-oxo-5α-lanosta-7,9(11)-diene-21-oic acid Usage And Synthesis

Chemical Properties

White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Poria cocos.

Biological Activity

Polyporenic acid C is a lanostane-type triterpenoid isolated from P. cocos. It induces apoptosis through the death receptor-mediated apoptotic pathway without the involvement of mitochondria. It has the potential to be used in lung cancer research.

target

PARP | Caspase | PI3K | Akt | p53

16α-Hydroxy-24-methylene-3-oxo-5α-lanosta-7,9(11)-diene-21-oic acidSupplier

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