Basic information Safety Supplier Related

Prostaglandin E1 Impurity 4

Basic information Safety Supplier Related

Prostaglandin E1 Impurity 4 Basic information

Product Name:
Prostaglandin E1 Impurity 4
Synonyms:
  • GMVPRGQOIOIIMI-JCPCGATGSA-N
  • 9-oxo-11α,15S-dihydroxy-(8β)-prost-13E-en-1-oic acid
  • OVINONIC ACID
  • 9-Oxo-11aloha,15S-dihydroxy-(8beta)-prost-13E-en-1-oic acid
  • 7-[(1S,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]heptanoic acid
  • (-)-8-epi-PGE1
  • (8β,13E,15S)-11α,15-Dihydroxy-9-oxoprost-13-en-1-oic acid
  • 8-Epiprostaglandin E1
CAS:
21003-46-3
MF:
C20H34O5
MW:
354.48
Mol File:
21003-46-3.mol
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Prostaglandin E1 Impurity 4 Chemical Properties

Melting point:
77-79 °C(Solv: ethyl acetate (141-78-6); hexane (110-54-3))
Boiling point:
529.3±50.0 °C(Predicted)
Density 
1.131±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: >100 mg/ml (from PGE1); DMSO: >50 mg/ml (from PGE1); Ethanol: >50 mg/ml (from PGE1); PBS pH 7.2: >1.6 mg/ml (from PGE1)
form 
A light yellow crystalline solid
pka
4.77±0.10(Predicted)
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Prostaglandin E1 Impurity 4 Usage And Synthesis

Description

Isoprostanes are a family of prostanoid molecules of non-cyclooxygenase origin. 8-iso Prostaglandin E1 (8-iso PGE1) is an isoprostane which is found in human semen at levels of 7 μg/ml. It is a pulmonary vasoconstrictor in anesthetized dogs with a potency similar to PGF.

Uses

Isoprostanes are a family of prostanoid molecules of non-cyclooxygenase origin. 8-iso Prostaglandin E1 (8-iso PGE1) is an isoprostane which is found in human semen at levels of 7 μg/ml. It is a pulmonary vasoconstrictor in anesthetized dogs with a potency similar to PGF2α.[Cayman Chemical]

Uses

8-Isoprostaglandin E1 has vasodilatory and electrophysiological actions porcine coronary artery. It also inhibits acetylcholine release from parasympathetic nerves innervating guinea-pig trachea mediation by prostanoid EP3 receptors.

Definition

ChEBI: 8-Isoprostaglandin E1 is a prostanoid.

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