13,14-DIHYDROPROSTAGLANDIN E1 CAS#: 58962-34-8

13,14-DIHYDROPROSTAGLANDIN E1 Basic information

Product Name:

13,14-DIHYDROPROSTAGLANDIN E1

Synonyms:

PROSTAGLANDIN F1-ALPHA, 6-KETO-
6-KETO-PROSTAGLANDIN F1ALPHA
6-OXO-9ALPHA,11ALPHA,15S-TRIHYDROXY-PROST-13E-EN-1-OIC ACID
6-KETOPROSTAGLANDIN F1A
6-keto Prostaglandin F1α Lipid Maps MS Standard
Epoprostenol Related CoMpound A
(9α,11α,13e,15s)-9,11,15-trihydroxy-6-oxoprosta-13-en-1-oic acid
7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentyl]-6-oxoheptanoic acid

CAS:

58962-34-8

MF:

C20H34O6

MW:

370.48

Mol File:

58962-34-8.mol

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13,14-DIHYDROPROSTAGLANDIN E1 Chemical Properties

Boiling point:: 575.3±50.0 °C(Predicted)
Density: 1.191±0.06 g/cm3(Predicted)
RTECS: UK8428300
storage temp.: −20°C
solubility: ethanol: 10 mg/mL, clear, faintly yellow
pka: 4.69±0.10(Predicted)
form: White to off-white solid.
BRN: 2821925

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Safety Information

Safety Statements: 22-24/25
WGK Germany: 3
F: 8-10
HS Code: 2937909000

MSDS

Language:English Provider:SigmaAldrich

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13,14-DIHYDROPROSTAGLANDIN E1 Usage And Synthesis

Description

6-keto prostaglandin F_1α (6-keto PGF_1α) is the inactive, non-enzymatic hydrolysis product of PGI₂. 6-keto PGF_1α serves as a useful marker of PGI₂ biosynthesis in vivo. When [³H]-PGI₂ is injected into healthy human males, 6.6% of the radioactivity is recovered from urine as [³H]-6-keto PGF_1α.

Uses

6-Ketoprostaglandin F1α is the stable hydrolysis product of prostacyclin (P839060), an eicosanoid which prevents the formation of platelet plugs and an effective vasodilator.

Definition

ChEBI: A prostaglandin Falpha that is prostaglandin F1alpha bearing a keto substituent at the 6-position.

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