Basic information Safety Supplier Related

Methyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate

Basic information Safety Supplier Related

Methyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate Basic information

Product Name:
Methyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate
Synonyms:
  • Methyl 2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methylthiazole-5-carboxylate
  • Methyl 2-(3-cyano-4-isobutoxyphenyl)-4-Methylthiazole-5-carboxylate
  • Methyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate
  • Febuxostat-54
  • Febuxostat Methyl Ester Impurity
  • Febuxostat Impurity 8/Febuxostat Methyl Ester/Methyl 2-(3-cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate
  • 2-(3-(ethoxycarbonyl)-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic acid
  • 5-Thiazolecarboxylic acid, 2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-, methyl ester
CAS:
923942-34-1
MF:
C17H18N2O3S
MW:
330.4
Mol File:
923942-34-1.mol
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Methyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate Chemical Properties

Melting point:
157-159°C
Boiling point:
486.8±55.0 °C(Predicted)
Density 
1.24
storage temp. 
2-8°C
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
0.95±0.10(Predicted)
form 
Solid
color 
White
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Methyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate Usage And Synthesis

Uses

Methyl 2-[3-Cyano-4-(2-methylpropoxy)phenyl]-4-methylthiazole-5-carboxylate is a 4-Methylthiazole-5-carboxylic Acid derivative as a potential inhibitor of mucin onco proteins for breast cancer therapy.Also, it is derived from Febuxostat (F229000), which is a xanthine oxidase/xanthine dehydrogenase inhibitor and used for treatment of hyperuricemia and chronic gout. 40-120 mg/day febuxostat was proven effective in lowering serum urate levels when administered to manage hyperuricemia in patients with gout.

Methyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylateSupplier

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