4-HYDROXYTHIOBENZAMIDE Chemical Properties

Melting point:

181-185℃

Boiling point:

320.4±44.0 °C(Predicted)

Density 

1.338±0.06 g/cm3(Predicted)

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

solubility 

DMSO (Slightly), Methanol (Slightly)

form 

Solid

pka

9.24±0.26(Predicted)

color 

Light Yellow

InChIKey

VDTNKXSVUGXUOJ-UHFFFAOYSA-N

CAS DataBase Reference

25984-63-8(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

20/21/22-36/37/38-43-22

Safety Statements 

26-36/37/39-36/37

HS Code 

29242990

4-HYDROXYTHIOBENZAMIDE Usage And Synthesis

Uses

4-Hydroxythiobenzamide(25984-63-8) is used in the synthesis of PPARα agonists used in increasing HDLc levels. Also used in the synthesis of potent CDK5 inhibitors in the treatment of Alzheimer’s disease.

Chemical Properties

4-Hydroxythiobenzamide has an appearance ranging from light orange to yellow to green, powder to crystalline, melting point 192 °C, soluble in methanol.

Uses

febuxostat intermediate

Uses

4-Hydroxythiobenzamide is used in the synthesis of PPARα agonists used in increasing HDLc levels. Also used in the synthesis of potent CDK5 inhibitors in the treatment of Alzheimer’s disease.

4-HYDROXYTHIOBENZAMIDE(25984-63-8)Related Product Information

• ethyl 2-(4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate
• ETHYL 2-(3-FORMYL-4-ISOBUTOXYPHENYL)-4-METHYLTHIAZOLE-5-CARBOXYLATE
• ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate
• Febuxostat
• 4-HYDROXYTHIOBENZAMIDE
• 4-METHOXYTHIOBENZAMIDE
• 2,3-DIHYDRO-1,4-BENZODIOXINE-6-CARBOTHIOAMIDE
• 6,7-DIMETHOXY-1,2,3,4-TETRAHYDROISOQUINOLINE-1-THIONE
• Tritiozine
• Vanitiolide
• 4-Ethoxybenzenecarbothioamide
• Benzamide
• THIOBENZAMIDE
• 4-[5-(TRIFLUOROMETHYL)PYRID-2-YLOXY]THIOBENZAMIDE
• 4-METHOXY-3-NITROBENZENE-1-CARBOTHIOAMIDE
• 2,3-DIHYDROBENZO[B]FURAN-5-CARBOTHIOAMIDE
• 1,3-BENZODIOXOLE-5-CARBOTHIOAMIDE
• 1-BENZYL-3-(TERT-BUTYL)-1H-PYRAZOLE-5-CARBOXYLIC ACID