ChemicalBook > Product Catalog > Pharmaceutical intermediates > Bulk Drug Intermediates > ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate
ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate
ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate Basic information
- Product Name:
- ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate
- Synonyms:
-
- ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate
- 2-(3-Formyl-4-hydroxy-phenyl)-4-methyl-thiazole-5-carboxylic acid ethyl ester
- Thiazolecarboxylicacid,2-(3-forMyl-4-hydroxyphenyl)-4-Methyl-,ethylester
- 5-carboxylato-1-ethyl-2-(3-forMyl-4-hydroxyphenyl)-4-Methyl-1H-1$l^{4},3-thiazol-1-yl
- Ethyl 2-(3-forMyl-4-hydroxyphenyl)-4-Methyl-5-Thiazolecarboxylate
- 5-carboxylato-1-ethyl-2-(3-forMyl-4-h
- ETHYL 2-(3-FORMYL-4-HYDROXYPHENYL)-4-METHYL-1,3-THIAZOLE-5-CARBOXYLATE
- Febuxostat-23
- CAS:
- 161798-01-2
- MF:
- C14H13NO4S
- MW:
- 291.32
- EINECS:
- 692-179-2
- Product Categories:
-
- Febuxostat intermediate
- 161798-01-2
- Mol File:
- 161798-01-2.mol
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ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate Chemical Properties
- Melting point:
- 116 °C
- Boiling point:
- 446.7±55.0 °C(Predicted)
- Density
- 1.335
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 6.81±0.20(Predicted)
- color
- Pale Yellow to Yellow
- CAS DataBase Reference
- 161798-01-2(CAS DataBase Reference)
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ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate Usage And Synthesis
Description
Ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate is a pharmaceutical intermediate used in the preparation of the xanthine oxidase inhibitor febuxostat, which is used in the treatment of hyperuricaemia and gout. It is also used in the synthesis of novel thiazolyl α-aminophosphonates.
Chemical Properties
Yellow or yellow powder
Uses
Ethyl 2-(3-Formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate is a product prepared via reaction 4-Hydroxybenzene-1-benzothiomide with ethyl-2-chloro acetoacetate. An antibacterial agent and antifungal activity against C.albicans.
ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5-carboxylateSupplier
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ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate(161798-01-2)Related Product Information
- Febuxostat
- Ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate
- isopropyl 2-(3-cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate
- 2,2'-[4-(2-Methylpropoxy)-1,3-phenylene]bis[4-Methyl-5-thiazolecarboxylic Acid 5,5'-DiMethyl Ester
- Febuxostat Impurity 14
- 2-(3-cyano-4-hydroxyphenyl)-4-methylthiazole-5-carboxylic acid
- Febuxostat Impurity 6
- 2,2'-[4-(2-Methylpropoxy)-1,3-phenylene]bis[4-Methyl-5-thiazolecarboxylic Acid
- 2-[3-Carboxy-4-(2-Methylpropoxy)phenyl]-4-Methyl-5-thiazolecarboxylic Acid
- 2-(3-cyano-4-propoxyphenyl)-4-methylthiazole-5-carboxylic acid
- Febuxostat Impurity 8
- 4-(2-Methylpropoxy)-1,3-benzenedicarbothioaMide
- Ethyl 2-(3-Cyano-4-hydroxyphenyl)-4-methyl-1,3-thiazole-5-carboxylate
- 3-Cyano-4-(2-methylpropoxy)benzenecarbothioamide
- Ethyl 2-(3-bromo-4-isobutoxyphenyl)- 4-methyl-5-thiazolecarboxylate
- 4-HYDROXYTHIOBENZAMIDE
- ETHYL 2-(3-FORMYL-4-ISOBUTOXYPHENYL)-4-METHYLTHIAZOLE-5-CARBOXYLATE
- ethyl 2-(4-hydroxyphenyl)-4-methyl thiazole-5-carboxylate