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3-Oxetaneethanol

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3-Oxetaneethanol Basic information

Product Name:
3-Oxetaneethanol
Synonyms:
  • 3-Oxetaneethanol
  • 2-(oxetan-3-yl)ethanol
  • 2-(oxetan-3-yl)ethano
  • 2-(oxetan-3-yl)ethan-1-ol
  • 3-(2-Hydroxyethyl)oxetane
  • 2-(3-Oxetanyl)ethanol
  • 3-Oxetaneethanol ISO 9001:2015 REACH
  • 2-(Oxetan-3-yl)ethanol - [X6653]
CAS:
251922-46-0
MF:
C5H10O2
MW:
102.13
Mol File:
251922-46-0.mol
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3-Oxetaneethanol Chemical Properties

Boiling point:
206℃
Density 
1.051
Flash point:
96℃
storage temp. 
2-8°C
pka
14.95±0.10(Predicted)
Appearance
Colorless to light yellow Liquid
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Safety Information

RIDADR 
UN1993
HS Code 
2905599890
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3-Oxetaneethanol Usage And Synthesis

Synthesis

569678-81-5

251922-46-0

Step D: A mixed system of 3-[2-(benzyloxy)ethyl]oxetane (550 mg, 2.86 mmol), Pd/C catalyst (350 mg), and anhydrous ethanol (5 mL) was subjected to a hydrogen atmosphere and stirred at room temperature for 48 hours. Upon completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated under reduced pressure to afford the target product 2-(oxetan-3-yl)ethanol (200 mg, 1.96 mmol, 66% yield) as a colorless oily liquid.

References

[1] Journal of the American Chemical Society,
[2] Journal of the American Chemical Society, 2009, vol. 131, p. 2786 - 2787
[3] Patent: WO2015/142903, 2015, A2. Location in patent: Page/Page column 93
[4] Patent: WO2015/140133, 2015, A1. Location in patent: Page/Page column 104; 105
[5] Chemical and Pharmaceutical Bulletin, 1999, vol. 47, # 9, p. 1334 - 1337

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