4-(4-fluoro-3-(piperazine-1-carbonyl)benzyl)phthalazin-1(2H)-one Chemical Properties

Density 

1.39±0.1 g/cm3(Predicted)

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

solubility 

DMSO (Slightly)

form 

Solid

pka

12.07±0.40(Predicted)

color 

White to Off-White

4-(4-fluoro-3-(piperazine-1-carbonyl)benzyl)phthalazin-1(2H)-one Usage And Synthesis

Uses

4-[[4-Fluoro-3-(1-piperazinylcarbonyl)phenyl]methyl]-1(2H)-phthalazinone is an intermediate used in the preparation of 4-benzyl-2H-phthalazin-1-ones that functions as PARP-1 and PARP-2 inhibitor.

4-(4-fluoro-3-(piperazine-1-carbonyl)benzyl)phthalazin-1(2H)-one(763111-47-3)Related Product Information

• Olaparib impurity 1
• Olaparib Imp.2
• 2,2'-Oxybis(nitrobenzene)
• Olaparib Impurity 30
• Olaparib Impurity 31
• 2-Propanone, 1-[4,5-dihydro-2-(4-methyl-1-piperazinyl)-4-thioxo-3H-1,5-benzodiazepin-3-ylidene]-
• Cyclopropanecarbonyl Chloride
• Olaparib Impurity 14
• 1-Hydroxybenzotriazole
• 1,1,3,3-Tetramethylurea
• 3-((4-Oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoic acid
• Cyclopropanecarboxylic acid
• tert-Butyl 1-piperazinecarboxylate
• tert-butyl 4-(cyclopropylcarbonyl)-1-piperazinecarboxylate
• tert-butyl 4-(2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)Methyl)benzoyl)piperazine-1-carboxylate
• 2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)Methyl)benzonitrile
• 5-Bromo-2-fluorobenzonitrile
• 3-oxo-1,3-dihydroisobenzofuran-1-ylphosphonic acid