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5-IODO-1,3-DIMETHYLURACIL

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5-IODO-1,3-DIMETHYLURACIL Basic information

Product Name:
5-IODO-1,3-DIMETHYLURACIL
Synonyms:
  • 5-IODO-1,3-DIMETHYLURACIL
  • 5-IODO-1,3-DIMETHYLURACIL, 99%%
  • 5-Iodo-1,3-dimethylpyrimidine-2,4-dione
  • 5-Iodo-1,3-diMethylpyriMidine-2,4(1H,3H)-dione
  • 5-Iodo-1,3-dimethyl-1H-pyrimidine-2,4-dione
  • 2,4(1H,3H)-Pyrimidinedione, 5-iodo-1,3-dimethyl-
  • 5-IODO-1,3-DIMETHYLURACIL USP/EP/BP
CAS:
40738-83-8
MF:
C6H7IN2O2
MW:
266.04
Product Categories:
  • pyrimidine
  • Heterocycle-Pyrimidine series
  • Building Blocks
  • Halogenated Heterocycles
  • Heterocyclic Building Blocks
  • Pyrimidines
  • PyrimidinesHeterocyclic Building Blocks
Mol File:
40738-83-8.mol
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5-IODO-1,3-DIMETHYLURACIL Chemical Properties

Melting point:
225 °C (dec.)(lit.)
Boiling point:
261.3±43.0 °C(Predicted)
Density 
2.04±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,2-8°C
solubility 
DMSO: soluble10mg/mL(lit.)
pka
-3.54±0.40(Predicted)
Sensitive 
Light Sensitive
CAS DataBase Reference
40738-83-8
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Safety Information

Hazard Codes 
Xn
Risk Statements 
20/21/22-42/43-63
Safety Statements 
22-26-36/37/39-45
WGK Germany 
3
HS Code 
29335990

MSDS

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5-IODO-1,3-DIMETHYLURACIL Usage And Synthesis

Uses

5-Iodo-1,3-dimethyluracil may be used for the synthesis of N-[2-[(1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)thio]-4-oxo[1]benzothieno[3,2-d]pyrimidin-3(4H)yl]methanesulfonamide.

General Description

The effect of 5-iodo-1,3-dimethyluracil on the incorporation of [125I] 5-iodo-2′-deoxyuridine [125I radiolabelled IdUrd] in DNA of cancer cells has been studied. Synthesis of 5-iodo-1,3-dimethyluracil from aromatic organomercurials; 5-(acetoxymercurio)-1,3-dimethyluracil or 5,5′-mercuriobis(1,3-dimethyluracil) has been reported.

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