5-Iodouracil Chemical Properties

Melting point:

274-276 °C (dec.) (lit.)

Density 

2.2076 (estimate)

storage temp. 

2-8°C

solubility 

Very faint turbidity in NH3aq. Soluble in 1M NaOH.

pka

7.02±0.10(Predicted)

form 

Fluffy Powder

color 

White to light yellow

Water Solubility 

SOLUBLE IN COLD WATER

Sensitive 

Light Sensitive

BRN 

4891

CAS DataBase Reference

696-07-1(CAS DataBase Reference)

NIST Chemistry Reference

5-Iodouracil(696-07-1)

EPA Substance Registry System

2,4(1H,3H)-Pyrimidinedione, 5-iodo- (696-07-1)

Safety Information

Hazard Codes 

T,Xi

Risk Statements 

46-20/21/22-36/37/38

Safety Statements 

53-22-26-36/37/39-45

RIDADR 

2811

WGK Germany 

3

RTECS 

YR0525000

Hazard Note 

Irritant/Carcinogenic/Light Sensitive

TSCA 

Yes

HazardClass 

6.1

PackingGroup 

III

HS Code 

29335990

MSDS

• Language:English Provider:2,4-Dihydroxy-5-iodopyrimidine
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

5-Iodouracil Usage And Synthesis

Chemical Properties

white to light yellow fluffy powder

Uses

5-Iodouracil is a halogenated pyrimidine that can be used in nucleoprotein photo-crosslinking via RNA substitution. 5-Iodouracil is used in thymidine phosphorylase targeted imaging and therapy. Studie s show that DNA N-glycosylase MED1 exhibited higher preference for 5-Iodouracil and halogenated bases over non-halogenated ones.

Uses

5-Iodouracil is a halogenated pyrimidine that can be used in nucleoprotein photo-crosslinking via RNA substitution. 5-Iodouracil is used in thymidine phosphorylase targeted imaging and therapy. Studies show that DNA N-glycosylase MED1 exhibited higher preference for 5-Iodouracil and halogenated bases over non-halogenated ones.

Definition

ChEBI: An organoiodine compound consisting of uracil having an iodo substituent at the 5-position.

5-Iodouracil(696-07-1)Related Product Information

• 3,5-Dihydroxybenzoic acid
• 1,3-Dihydroxyacetone
• 1-Hydroxyethylidene-1,1-diphosphonic acid
• Butylated Hydroxytoluene
• Uracil
• Solvent Red 43
• Triclosan
• 2-ISOPROPYL-6-METHYL-4-PYRIMIDINOL
• 5-IODOPYRIMIDINE
• 5-IODOURIDINE
• Idoxuridine
• 5-IODO-1,3-DIMETHYLURACIL
• Fialuridine
• 6-IODOURACIL
• 3',5'-DIACETYL-5-IODO-2'-DEOXYURIDINE
• (S)-(-)-5-IODOWILLARDIINE
• N-blocked-5'-O-DMT 3'-CED iododeoxyuridine phosphoramidite
• 5-IODO-2',3'-DIDEOXYURIDINE