O-(2-AMINOETHYL)-L-SERINE HYDROCHLORIDE
O-(2-AMINOETHYL)-L-SERINE HYDROCHLORIDE Basic information
- Product Name:
- O-(2-AMINOETHYL)-L-SERINE HYDROCHLORIDE
- Synonyms:
-
- H-SER(ETNH2)-OH HCL
- H-LYS[*4(<-O)]-OH HCL
- L-4-OXALYSINE HCL
- (S)-(+)-2-AMINO-3-(2-AMINOETHOXY)PROPANOIC ACID, MONOHYDROCHLORIDE
- O-(2-AMINOETHYL)-L-SERINE HYDROCHLORIDE
- L-4-Oxalysine (hydrochloride)
- (S)-(+)-2-AMINO-3-(2-AMINOETHOXY)-PROPAN OIC ACID HYDROCHLORIDE, 98%
- 4-OXY-L-LYSINE HYDROCHLORIDE
- CAS:
- 118021-35-5
- MF:
- C5H13ClN2O3
- MW:
- 184.62
- Product Categories:
-
- Others
- Peptide Synthesis
- Unnatural Amino Acid Derivatives
- Mol File:
- 118021-35-5.mol
O-(2-AMINOETHYL)-L-SERINE HYDROCHLORIDE Chemical Properties
- Melting point:
- 212-216 °C(lit.)
- alpha
- +4.0～+8.0°(c=10,dilHCl)(D/20)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- form
- Solid
- color
- White to off-white
MSDS
- Language:English Provider:SigmaAldrich
O-(2-AMINOETHYL)-L-SERINE HYDROCHLORIDE Usage And Synthesis
Uses
L-4-Oxalysine hydrochloride is a natural product isolated from the culture media of Streptomyces roseovirdofuscus in China which has shown antitumor activities.
Biological Activity
L-4-Oxalysine hydrochloride is a natural substance isolated from the culture medium of Streptomyces in China and has anticancer activity.
in vitro
L-4-oxalysine functionally antagonizes the a-fetoprotein-induced suppression of the mitogen- and one-way mixed lymphocyte culture-induced proliferation of spleen lymphocytes and interleukin-6 production by these cells in mice bearing the hepatoma-22 tumor.
in vivo
L-4-oxalysine inhibits the proliferation of some mouse implanted tumors and pulmonary metastasis of mouse Lewis lung carcinoma.
References
[1] Dai ZQ, et al. Effect of L-4-oxalysine on ultrastructures of liver cells in mice. Zhongguo Yao Li Xue Bao. 1991 Jul;12(4):336-40. PMID:1807083
[2] Wang XW, et al. Immunostimulatory action of L-4-oxalysine counteracts immunosuppression induced by alpha-fetoprotein. Eur J Pharmacol. 1998 Jun 12;351(1):105-11. DOI:10.1016/s0014-2999(98)00277-5
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