LOXIGLUMIDE
LOXIGLUMIDE Basic information
- Product Name:
- LOXIGLUMIDE
- Synonyms:
-
- 4-[(3,4-dichlorobenzoyl)amino]-5-[3-methoxypropyl(pentyl)amino]-5-oxopentanoic acid
- 4-[(3,4-dichlorophenyl)carbonylamino]-5-[3-methoxypropyl(pentyl)amino]-5-oxo-pentanoic acid
- 5-[amyl(3-methoxypropyl)amino]-4-[(3,4-dichlorobenzoyl)amino]-5-keto-valeric acid
- LoxigluMide (CR1505)
- LOXIGLUMIDE
- CS-162
- Loxiglumide, >98%
- (+-)-4-((3,4-dichlorobenzoyl)amino)-5-((3-methoxypropyl)pentylamino)-5-oxope
- CAS:
- 107097-80-3
- MF:
- C21H30Cl2N2O5
- MW:
- 461.38
- Product Categories:
-
- Inhibitors
- Mol File:
- 107097-80-3.mol
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LOXIGLUMIDE Chemical Properties
- Melting point:
- 113-115℃
- Boiling point:
- 632.2±55.0 °C(Predicted)
- Density
- 1.233±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO: ≥5mg/mL
- pka
- pKa ~5(at 25℃)
- form
- powder
- color
- white to beige
- CAS DataBase Reference
- 107097-80-3
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LOXIGLUMIDE Usage And Synthesis
Uses
Loxiglumide is a CCK1 antagonist. Suppresses CCK-induced proliferation of acinar cells. Inhibits pancreatic secretion of digestive enzymes. Active in vivo.
Definition
ChEBI: Loxiglumide is an organic molecular entity.
Biochem/physiol Actions
Loxiglumide is a small-molecule antagonist of the cholecystokinin receptor CCKA. Loxiglumide inhibits pancreatic secretion of digestive enzymes, and also blocks CCK-induced gastric secretions and emptying.
Safety Profile
A poison by intravenous. Moderately toxic by ingestion, intraperitoneal, and subcutaneous routes. When heated to decomposition it emits toxic vapors of NOx and Cl-.
storage
Store at -20°C
LOXIGLUMIDESupplier
Shanghai Boyle Chemical Co., Ltd.
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