CGP 42112 Chemical Properties

Density 

1.39±0.1 g/cm3(Predicted)

storage temp. 

-20°C

solubility 

DMSO:350.0(Max Conc. mg/mL);332.64(Max Conc. mM)

pka

3.72±0.22(Predicted)

form 

solid

color 

white

Water Solubility 

Soluble to 1 mg/ml in water

BRN 

8184948

Safety Information

Safety Statements 

22-24/25

WGK Germany 

3

F 

10

MSDS

• Language:English Provider:SigmaAldrich

CGP 42112 Usage And Synthesis

Definition

ChEBI: CGP-42112A is a hexapeptide consisting of L-tyrosine, L-lysine, L-histidine, L-proline and L-isoleucine amino acid residues coupled in sequence and in which the amino group of the L-tyrosyl residue is substituted by a (pyridin-3-ylcarbonyl)nitrilo group and in which the L-lysyl side chain amino group is substituted by a {N(2)-[(benzyloxy)carbonyl]-L-arginyl}nitrilo group. It is a potent angiotensin II receptor type 2 (AT2 receptor) agonist. It has a role as an angiotensin receptor agonist, a vasodilator agent, an antineoplastic agent, an anti-inflammatory agent and a neuroprotective agent. It is an oligopeptide, a benzyl ester and a pyridinecarboxamide.

Biochem/physiol Actions

Potent AT2 angiotensin II receptor agonist.

storage

Store at -20°C

CGP 42112(127060-75-7)Related Product Information

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