H-PRO-VAL-OH Chemical Properties

Melting point:

221 °C

Boiling point:

451.1±45.0 °C(Predicted)

Density 

1.150±0.06 g/cm3(Predicted)

storage temp. 

-15°C

pka

3.54±0.10(Predicted)

Sequence

Pro-Val

Safety Information

Hazard Codes 

Xn

Risk Statements 

22

H-PRO-VAL-OH Usage And Synthesis

Uses

H-Pro-Val-OH is a deprotonation dipeptide containing proline, which can catalyze the Michael addition reaction of acetone to trans-β-nitrostyrene. H-Pro Val OH can also serve as a substrate for fibroblast enzymes and prolinase, and has potential applications in biochemical analysis[1][2][3][4].

References

[1] Harrison AG, et al. Fragmentation reactions of deprotonated peptides containing proline. The proline effect. J Mass Spectrom. 2005 Sep;40(9):1173-86. DOI:10.1002/jms.891
[2] Davie EA, et al. Asymmetric catalysis mediated by synthetic peptides. Chem Rev. 2007 Dec;107(12):5759-812. DOI:10.1021/cr068377w
[3] Uramatsu M, et al. Different effects of sulfur amino acids on prolidase and prolinase activity in normal and prolidase-deficient human erythrocytes. Clin Chim Acta. 2007 Jan;375(1-2):129-35. DOI:10.1016/j.cca.2006.06.027
[4] Myara I, et al. Determination of prolinase activity in plasma. Application to liver disease and its relation with prolidase activity. Clin Biochem. 1985 Aug;18(4):220-3. DOI:10.1016/s0009-9120(85)80043-6

H-PRO-VAL-OH(52899-09-9)Related Product Information

• DIPROTIN A
• α-MSH (11-13) (free acid)
• H-PHE-TYR-GLY-PRO-VAL-OH
• RRKASGPPV
• H-TYR-PRO-PHE-VAL-GLU-PRO-ILE-OH
• MEOSUC-ALA-ALA-PRO-VAL-OH
• H-PRO-VAL-OH
• H-GLY-PHE-GLN-GLU-ALA-TYR-ARG-ARG-PHE-TYR-GLY-PRO-VAL-OH
• H-PRO-ILE-OH
• CGP 42112
• H-GLU-GLY-VAL-TYR-VAL-HIS-PRO-VAL-OH
• H-VAL-SER-SER-ASN-ILE-SER-GLU-ASP-PRO-VAL-PRO-VAL-OH
• (DES-ASP1,ILE8)-ANGIOTENSIN II
• BETA-CASOMORPHIN (BOVINE)
• ALPHA-SUBSTANCE IB
• PYR-VAL-OH
• ANGIOTENSIN III ANTIPEPTIDE
• H-SER-TYR-SER-MET-GLU-HIS-PHE-ARG-TRP-GLY-LYS-PRO-VAL-OH