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Timolol EP Impurity H

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Timolol EP Impurity H Basic information

Product Name:
Timolol EP Impurity H
Synonyms:
  • 2-[3-(tert-butylamino)-2-hydroxypropyl]-4-morpholin-4-yl-1,2,5-thiadiazol-3-one
  • Timolol EP Impurity H HCl
  • Timolol Impurity 8(Timolol EP Impurity H)
  • Timolol EP Impurity H
  • 2-(3-(tert-Butylamino)-2-hydroxypropyl)-4-morpholino-1,2,5-thiadiazol-3(2H)-one (>
  • 1,2,5-Thiadiazol-3(2H)-one, 2-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropyl]-4-(4-morpholinyl)-
  • 1-(2-(tert-Butylamino)-2-hydroxyethyl)-4-morpholino-1H-imidazol-5(2H)-one
  • 2-(3-(tert-Butylamino)-2-hydroxypropyl)-4-morpholino-1,2,5-thiadiazol-3(2H)-one (>90%)
CAS:
158636-97-6
MF:
C13H24N4O3S
MW:
316.42
Mol File:
158636-97-6.mol
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Timolol EP Impurity H Chemical Properties

Boiling point:
466.5±55.0 °C(Predicted)
Density 
1.35±0.1 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
13.86±0.20(Predicted)
color 
Light Yellow to Brown Waxy
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Timolol EP Impurity H Usage And Synthesis

Uses

2-(3-(tert-Butylamino)-2-hydroxypropyl)-4-morpholino-1,2,5-thiadiazol-3(2H)-one is a impurity of Timolol (T443710), an antihypertensive; antiarrhythmic (class II); antianginal; antiglaucoma agent.

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