4-[1-(4-cyano-3-trifluoromethyl-phenylcarbamoyl)-1-methyl-ethylamino]-2-fluoro-N- Chemical Properties

Boiling point:

616.2±55.0 °C(Predicted)

Density 

1.36±0.1 g/cm3(Predicted)

solubility 

DMSO (Slightly), Methanol (Slightly)

form 

Solid

pka

13?+-.0.70(Predicted)

color 

White to Off-White

4-[1-(4-cyano-3-trifluoromethyl-phenylcarbamoyl)-1-methyl-ethylamino]-2-fluoro-N- Usage And Synthesis

Uses

4-[[2-[[4-Cyano-3-(trifluoromethyl)phenyl]amino]-1,1-dimethyl-2-oxoethyl]amino]-2-fluoro-N-methyl-benzamide is an impurity of Enzalutamide (M199800), an androgen-receptor antagonist that blocks androgens from binding to the androgen receptor and prevents nuclear translocation and co-activator recruitment of the ligand-receptor complex.

4-[1-(4-cyano-3-trifluoromethyl-phenylcarbamoyl)-1-methyl-ethylamino]-2-fluoro-N-(1289942-55-7)Related Product Information

• Enzalutamide Impurity 20
• 4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluorobenzoic acid methyl ester
• Enzalutamide
• EnzalutaMide IMpurity
• methyl 2-fluoro-4-((1-methoxy-2-methyl-1-oxopropan-2-yl)amino)benzoate
• 4-Bromo-2-fluorobenzoic acid
• 4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl]-N-methylbenzamide
• 4-[3-[4-Cyano-3-(trifluoroMethyl)phenyl]-5,5-diMethyl-4-oxo-2-thioxo-1-iMidazolidinyl]-2-fluoro-N-(Methyl-d3)benzaMide
• Enzalutamide
• Methyl 4-bromo-2-fluorobenzoate
• 4-(2-CYANOPROPAN-2-YLAMINO)-2-FLUORO-N-METHYLBENZAMIDE
• Enzalutamide carboxylic acid
• N-desMethyl EnzalutaMide
• [2H6]-Enzalutamide
• Enzalutamide Impurity 7
• 4-isothiocyanato-2-(trifluoroMethyl)benzonitrile
• Enzalutamide Impurity 7
• 4-amino-2-fluoro-N-methylbenzamide