N-desMethyl EnzalutaMide Chemical Properties

Melting point:

>230oC (dec.)

Boiling point:

572.4±60.0 °C(Predicted)

Density 

1.55±0.1 g/cm3(Predicted)

storage temp. 

Amber Vial, Refrigerator

solubility 

Chloroform (Slightly), DMSO (Slightly), Methanol (Very Slightly, Heated)

pka

14.86±0.50(Predicted)

form 

Solid

color 

White to Off-White

Stability:

Light Sensitive

N-desMethyl EnzalutaMide Usage And Synthesis

Uses

4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluorobenzamide is used in the treatment of disorders involving androgen, estrogen and progesterone receptors.

Uses

N-desMethyl EnzalutaMide is used in the treatment of disorders involving androgen, estrogen and progesterone receptors.

Definition

ChEBI: N-desmethylenzalutamide is a benzamide obtained by formal condensation of the carboxy group of 4-{3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl}-2-fluorobenzoic acid with ammonia. It has a role as an antineoplastic agent and an androgen antagonist. It is a member of benzamides, an imidazolidinone, a nitrile, a thiocarbonyl compound, a member of (trifluoromethyl)benzenes and a member of monofluorobenzenes.

N-desMethyl EnzalutaMide(1242137-16-1)Related Product Information

• Enzalutamide
• Enzalutamide
• Enzalutamide carboxylic acid
• Oxathiolan 5fu-.B.
• 4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluorobenzoic acid methyl ester
• EnzalutaMide IMpurity
• methyl 2-fluoro-4-((1-methoxy-2-methyl-1-oxopropan-2-yl)amino)benzoate
• 4-Bromo-2-fluorobenzoic acid
• 4-[3-(4-Cyano-3-trifluoromethylphenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl]-N-methylbenzamide
• 4-[3-[4-Cyano-3-(trifluoroMethyl)phenyl]-5,5-diMethyl-4-oxo-2-thioxo-1-iMidazolidinyl]-2-fluoro-N-(Methyl-d3)benzaMide
• Methyl 4-bromo-2-fluorobenzoate
• 4-(2-CYANOPROPAN-2-YLAMINO)-2-FLUORO-N-METHYLBENZAMIDE
• [2H6]-Enzalutamide
• Enzalutamide Impurity 7
• 4-isothiocyanato-2-(trifluoroMethyl)benzonitrile
• Enzalutamide Impurity 7
• 4-[1-(4-cyano-3-trifluoromethyl-phenylcarbamoyl)-1-methyl-ethylamino]-2-fluoro-N-
• 4-amino-2-fluoro-N-methylbenzamide