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3-ACETYLDEOXYNIVALENOL

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3-ACETYLDEOXYNIVALENOL Basic information

Product Name:
3-ACETYLDEOXYNIVALENOL
Synonyms:
  • 3-acetyldeoxynivalenol solution
  • 3α-acetoxy-7α,15-dihydroxy-12,13-epoxytrichothec-9-en-8-one
  • 3-ACETYL-DEOXYNIVALENOL SOLUTION (100&MU
  • 3α-Acetylvomitoxin, 3-AcDON, 3α-Acetoxy-7α,15-dihydroxy-12,13-epoxytrichothec-9-en-8-one
  • 3α-Acetylvomitoxin, 3-AcDON, 3-ADON, 3α-Acetoxy-7α,15-dihydroxy-12,13-epoxytrichothec-9-en-8-one
  • 12,13-Epoxy-3α-acetoxy-7α,15-dihydroxytrichothec-9-en-8-one
  • 3α-Acetoxy-7α,15-dihydroxy-12,13-epoxytrichotheca-9-ene-8-one
  • DON-3-acetate
CAS:
50722-38-8
MF:
C17H22O7
MW:
338.35
EINECS:
621-771-5
Product Categories:
  • mycotoxin
Mol File:
50722-38-8.mol
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3-ACETYLDEOXYNIVALENOL Chemical Properties

Melting point:
185.75°C
Boiling point:
394.5°C (rough estimate)
Density 
1.2179 (rough estimate)
refractive index 
1.4790 (estimate)
Flash point:
2 °C
storage temp. 
-20°C
solubility 
DMF: 30 mg/ml; DMSO: 25 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 10 mg/ml
pka
11.84±0.70(Predicted)
LogP
-0.448 (est)
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Safety Information

Hazard Codes 
T,Xn,F
Risk Statements 
23/24/25-36-20/21/22-11
Safety Statements 
36/37-45-26-16
RIDADR 
UN 2811 6.1/PG 2
WGK Germany 
3
RTECS 
YD0150000
HazardClass 
6.1(a)
PackingGroup 
I
HS Code 
29329990

MSDS

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3-ACETYLDEOXYNIVALENOL Usage And Synthesis

Chemical Properties

Solid

Uses

3-Acetyldeoxynivalenol solution may be used as an analytical reference standard for the quantification of the analyte in bovine milk using liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS).

Uses

3-Acetyldeoxynivalenol is a trichothecene mycotoxin that is produced in a plant-pathogenic fungus, Fusarium graminearum Schwabe.

Definition

ChEBI: 3-acetyldeoxynivalenol is a trichothecene mycotoxin that is deoxynivalenol acetylated on the oxygen at C-3. A skin and eye irritant, along with its 15-acetyl regioisomer and its parent deoxynivalenol it is considered among the most commonly and widely distributed cereal contaminants. It has a role as an epitope and a mycotoxin. It is functionally related to a deoxynivalenol.

General Description

3-Acetyldeoxynivalenol is a trichothecene mycotoxin, secreted by Fusarium species. It stimulates the activation of c-Jun N-terminal kinase (JNK)/ p38 mitogen-activated protein kinases and prevents protein synthesis. 3-Acetyldeoxynivalenol is a weak inducer of apoptosis.

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