2-HYDROXYHEXADECANOIC ACID Chemical Properties

Melting point:

86 °C

Boiling point:

405.5±18.0 °C(Predicted)

Density 

0.955±0.06 g/cm3(Predicted)

storage temp. 

2-8°C

solubility 

very faint turbidity in Methanol

form 

powder to crystal

pka

3.86±0.21(Predicted)

color 

White to Almost white

LogP

6.210 (est)

CAS DataBase Reference

764-67-0(CAS DataBase Reference)

Safety Information

WGK Germany 

3

HS Code 

2918.19.9000

MSDS

• Language:English Provider:SigmaAldrich

2-HYDROXYHEXADECANOIC ACID Usage And Synthesis

Uses

2-Hydroxyhexadecanoic Acid is used in the investigation of role of hypoxia in mechanism of action of elisidepsin which reduces drug efficiency by inhibiting hydroxylation and altering structure of lipid rafts in human SKBR-3, MCF-7, MDA-MB-453 cell lines. Also used in the studies on the antiviral activity of hydroxy fatty acids.

Definition

ChEBI: A 2-hydroxy fatty acid comprising a C16 straight chain carrying a hydroxy substituent at position 2.

Biochem/physiol Actions

2-Hydroxyhexadecanoic acid (2OH-HDA) is used as a representative of the saturated long-chain hydroxyl fatty acids group, members of which have potential roles in anti-inflammatory action, neuroprotection, and bactericide and anti-cancer defense.

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