9-KETO FLUPROSTENOL Chemical Properties

Boiling point:

607.6±55.0 °C(Predicted)

Density 

1.331±0.06 g/cm3(Predicted)

solubility 

Ethanol: Miscible; PBS (7.2): 10 mg/ml

pka

4.75±0.10(Predicted)

9-KETO FLUPROSTENOL Usage And Synthesis

Description

9-keto Fluprostenol is an analog of prostaglandin E₂ (PGE₂) with structural modifications intended to give it a prolonged half-life and greater potency. Fluprostenol is a well-studied, potent analog of PGF_2α and acts primarily through the FP receptor. Oxidation at C-9 of fluprostenol yields 9-keto fluprostenol. It is anticipated that this analog will have strong affinity for EP receptors and act as a PGE₂ agonist. However, no studies on the pharmacology of this compound have been published to date.

Uses

9-keto Fluprostenol is an analog of prostaglandin E2 (PGE2) with structural modifications intended to give it a prolonged half-life and greater potency. Fluprostenol is a well-studied, potent analog of PGF2α and acts primarily through the FP receptor. Oxidation at C-9 of fluprostenol yields 9-keto fluprostenol. It is anticipated that this analog will have strong affinity for EP receptors and act as a PGE2 agonist. However, no studies on the pharmacology of this compound have been published to date.

Uses

9-Keto Fluprostenol is an impurity of Fluprostenol (F500753), a FP prostaglandin receptor.

9-KETO FLUPROSTENOL(156406-33-6)Related Product Information

• Iodoethane
• Ethyl bromoacetate
• 15(S)-Fluprostenol isopropyl ester
• Travoprost
• 15-KETO FLUPROSTENOL
• 5,6-trans Travoprost
• 3-Trifluoromethylphenol
• 15-Keto Travoprost
• (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-enyl]cyclopentyl]-N-(1,3-dihydroxypropan-2-yl)hept-5-enamide
• (+)-Fluprostenol
• 9-keto Fluprostenol isopropyl ester
• 9-KETO FLUPROSTENOL
• Fluprostenol