Basic information Safety Supplier Related

Fluprostenol

Basic information Safety Supplier Related

Fluprostenol Basic information

Product Name:
Fluprostenol
Synonyms:
  • (+/-)-16-(3-TRIFLUOROMETHYLPHENOXY)TETRANORPROSTAGLANDIN F2ALPHA
  • (+/-)16-(M-TRIFLUOROMETHYLPHENOXY)-TETRANOR-PROSTAGLANDIN F2ALPHA
  • (+/-)-9ALPHA,11ALPHA,15R-TRIHYDROXY-16-(3-(TRIFLUOROMETHYL)PHENOXY)-17,18,19, 20-TETRANORPROSTA 5Z,13E-DIEN-1-OIC ACID
  • FLUPROSTENOL
  • (±)-16-(3-trifluoromethylphenoxy)tetranorprostaglandin f2α
  • FLUPROSTENOL, ETHANOL SOLUTION
  • WWSWYXNVCBLWNZ-QIZQQNKQSA-N
  • (5Z)-rel-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentyl]-5-heptenoic acid
CAS:
40666-16-8
MF:
C23H29F3O6
MW:
458.47
EINECS:
255-029-3
Product Categories:
  • prost
Mol File:
40666-16-8.mol
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Fluprostenol Chemical Properties

Boiling point:
608.0±55.0 °C(Predicted)
Density 
1.335
storage temp. 
−20°C
form 
Colorless oil dissolved in ethanol (1mg/100μl).
pka
4.76±0.10(Predicted)
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Safety Information

Hazard Codes 
F
Risk Statements 
11
Safety Statements 
7-16
RIDADR 
UN 1170 3/PG 2
WGK Germany 
1

MSDS

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Fluprostenol Usage And Synthesis

Uses

Fluprostenol is a prostaglandin F (FP) receptor agonist.

Definition

ChEBI: Fluprostenol is an organofluorine compound that is racemic prostaglandin F2alpha in which the pentyl group is replaced by a 3-(trifluoromethyl)phenoxymethyl group. A synthetic analogue of prostaglandin F2alpha, ophthalmic solutions of its isopropyl ester prodrug, travoprost, are used as a topical medication for controlling the progression of open-angle glaucoma and ocular hypertension, by reducing intraocular pressure. The isopropyl ester group of travoprost is hydrolysed to the biologically active free acid by esterases in the cornea. It has a role as an antiglaucoma drug, an antihypertensive agent, a prostaglandin receptor agonist, a female contraceptive drug and an abortifacient. It is a prostaglandins Falpha, a hydroxy monocarboxylic acid and a member of (trifluoromethyl)benzenes.

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