(R)-(-)-1,3-Butanediol Chemical Properties

Melting point:

0.07°C (estimate)

alpha 

-31 º (c=1 in EtOH)

Boiling point:

107-110 °C/23 mmHg (lit.)

Density 

1.005 g/mL at 25 °C (lit.)

vapor density 

3.1 (vs air)

vapor pressure 

0.06 mm Hg ( 20 °C)

refractive index 

1.44

Flash point:

250 °F

storage temp. 

Inert atmosphere,Room Temperature

solubility 

Chloroform, Ethanol

form 

Oil

pka

14.83±0.20(Predicted)

color 

Clear Colourless

optical activity

[α]21/D 31.0°, c = 1 in ethanol

Water Solubility 

Fully miscible in water.

Sensitive 

Hygroscopic

BRN 

1718944

InChIKey

PUPZLCDOIYMWBV-SCSAIBSYSA-N

LogP

-0.9 at 25℃

CAS DataBase Reference

6290-03-5(CAS DataBase Reference)

NIST Chemistry Reference

1,3-Butanediol, (R)-(6290-03-5)

EPA Substance Registry System

1,3-Butanediol, (3R)- (6290-03-5)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36

WGK Germany 

3

RTECS 

EK0440000

F 

3-10

Autoignition Temperature

741 °F

Hazard Note 

Irritant

HS Code 

29053920

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

(R)-(-)-1,3-Butanediol Usage And Synthesis

Chemical Properties

Colorless to light yellow liqui

Uses

(R)-(-)-1,3-Butanediol is used as a solvent for food flavoring agents and is a co-monomer used in certain polyurethane and polyester resins.

Application

(R)-(-)-1,3-Butanediol is a chiral reagent used in the synthesis of pharmaceuticals including the preparation of (-)-tarchonanthuslactone, a δ-lactone skeleton based compound with antiroliferative activity on cancer cell.

Definition

ChEBI: A butane-1,3-diol of R-configuration.

Flammability and Explosibility

Not classified

References

Novaes, L. et al.: ChemMedChem., 10, 1687 (2015);
Akinobu Matsuyama; Hiroaki Yamamoto; Naoki Kawada; Yoshinori Kobayashi. Industrial production of (R)-1,3-butanediol by new biocatalysts.Journal of Molecular Catalysis B: Enzymatic.2001,11(4-6), 513-521.
Naoki Ichikawa; Satoshi Sato; Ryoji Takahashi; Toshiaki Sodesawa; Harunori Fujita; Takashi Atoguchi; Akinobu Shiga. Theoretical investigation of 1,3-butanediol adsorption on an oxygen-defected CeO2(111) surface.Journal of Catalysis.2006,239(1), 13-22.

(R)-(-)-1,3-Butanediol(6290-03-5)Related Product Information

• 2,3-Butanediol
• 1,4-Butanediol
• 2-Butoxyethanol
• 2-Butyne-1,4-diol
• DI(PROPYLENE GLYCOL) BUTYL ETHER
• 2-Butoxyethyl acetate
• Oxytetracycline dihydrate
• CYMARIN
• 1,2:5,6-Bis-O-(1-methylethylidene)-D-mannitol
• Prednisone
• CORTISONE
• Digitoxin
• (+/-)-1,2-BUTANEDIOL,1,2-BUTANEDIOL
• 1,3-Butanediol
• 2,2,4,4-TETRAMETHYL-1,3-CYCLOBUTANEDIOL
• G-STROPHANTHIN
• Cortisone acetate
• (S,S)-(+)-2,3-BUTANEDIOL,(S,S)-2,3-BUTANEDIOL