Cyanine5.5 DBCO Chemical Properties

solubility 

good in DMF, DMSO, chlorinated organic solvents

form 

Solid

color 

Purple to purplish red

Appearance

dark colored solid

Cyanine5.5 DBCO Usage And Synthesis

Description

Strain promoted alkyne azide cycloaddition (SPAAC) between strained cycloalkynes and azides is a useful bioconjugation method that eliminates the need for copper catalyst necessary for classical CuAAC click chemistry.

Cyanine5.5 DBCO is a cyclooctyne product containing Cyanine5.5 fluorescent dye. This fluorophore is used in bioimaging, biodistribution studies, and microscopy.

Cyanine5.5 DBCO can be used to conjugate the fluorophore with various azides.

Uses

Dibenzocyclooctyne-Cy5.5 (DBCO-Cy5.5) is a fluorescent dye. Dibenzocyclooctyne-Cy5.5 can be used to syntheses calcium-binding near-infrared fluorescent nanoprobe for bone tissue imaging[1].

References

[1] Yong Geun Lim, et al. Calcium-binding near-infrared fluorescent nanoprobe for bone tissue imaging. Journal of Industrial and Engineering Chemistry. Volume 89, 25 September 2020, Pages 442-447

Abs/Em Maxima

684/710 nm

Fluoresene quantum yield

0.2

Extinction Coefficient

198000

Cyanine5.5 DBCO(2643308-61-4)Related Product Information

• Gadoteridol
• Cyanine3 tetrazine
• Cyanine5 tetrazine
• diSulfo-Cy5 DBCO(Methyl)
• Cyanine7 DBCO
• Cyanine5 DBCO
• diSulfo-Cy3 DBCO(Methyl)
• diSulfo-Cy5 azide
• ICG-DBCO
• Cyanine5.5 tetrazine
• Cyanine 7 tetrazine
• Cyanine3 DBCO
• disulfo-ICG-DBCO
• disulfo-ICG-azide
• triSulfo-Cy5.5 DBCO
• ICG-azide