Cyanine5 DBCO Chemical Properties

solubility 

good in DMF, DMSO, chlorinated organic solvents, practically insoluble in water (<1 uM, < 1 mg/L)

Appearance

dark blue solid

InChIKey

IWKWVRXEKCOQTG-UHFFFAOYSA-O

SMILES

C(N1C(C(C)(C)C2=CC=CC=C12)=CC=CC=CC1C(C2=CC=CC=C2[N+]=1C)(C)C)CCCCC(=O)NCCC(N1CC2=CC=CC=C2C#CC2=CC=CC=C12)=O

Cyanine5 DBCO Usage And Synthesis

Description

A derivative of Cyanine5 red-emitting fluorophore possessing DBCO (dibenzocyclooctyne, also known as ADIBO, azodibenzocyclooctyne) group for copper free click chemistry.

Strained cycloalkynes, such as cyclooctynes, react with azides very rapidly in the absence of copper catalyst in a strain-promoted alkyne-azide cycloaddition (SPAAC). This reaction is very fast, mild, and biocompatible.

Compared to other cycloalkynes, DBCO provide among the fastest reaction kinetics, still possessing good stability.

Abs/Em Maxima

646/662 nm

Fluoresene quantum yield

0.2

Extinction Coefficient

250000

Cyanine5 DBCO(2182601-71-2)Related Product Information

• disulfo-ICG-DBCO
• disulfo-ICG-azide
• triSulfo-Cy5.5 DBCO
• ICG-azide
• Cyanine5.5 DBCO
• Cyanine5 carboxylic acid
• Cyanine5 alkyne
• Gadoteridol
• Cyanine3 tetrazine
• diSulfo-Cy5 DBCO(Methyl)
• Cyanine7 DBCO
• diSulfo-Cy3 DBCO(Methyl)
• diSulfo-Cy5 azide
• ICG-DBCO
• Cyanine5.5 tetrazine
• Cyanine 7 tetrazine
• Cyanine3 DBCO
• Cyanine5 tetrazine