Basic information Safety Supplier Related

2',5'-DIDEOXYADENOSINE

Basic information Safety Supplier Related

2',5'-DIDEOXYADENOSINE Basic information

Product Name:
2',5'-DIDEOXYADENOSINE
Synonyms:
  • 2',5'-DD-ADO
  • 5-(6-AMINOPURIN-9-YL)-2-METHYLTETRAHYDROFURAN-3-OL
  • (2R,3S,5R)-5-(6-aMino-9H-purin-9-yl)-2-Methyltetrahydrofuran-3-ol
  • NSC 95943
  • NSC 95943 2',5'-DIDEOXYADENOSINE
  • phosphoric acid [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-2-oxolanyl]methyl [hydroxy(phosphonooxy)phosphoryl] [(2R,3S,4R,5R)-3,4,5,6-tetrahydroxy-1-oxohexan-2-yl] ester
  • 2,5-Dideoxyadenosine - CAS 6698-26-6 - Calbiochem
  • Adenosine, 2',5'-dideoxy-
CAS:
6698-26-6
MF:
C10H13N5O2
MW:
235.24
Product Categories:
  • Adenylate cyclaseG Proteins and Cyclic Nucleotides
  • Adenylyl Cyclase Inhibitors
  • A to
  • Cyclic Nucleotide Metabolism
  • Enzyme Inhibitors by Enzyme
Mol File:
6698-26-6.mol
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2',5'-DIDEOXYADENOSINE Chemical Properties

Boiling point:
547.0±60.0 °C(Predicted)
Density 
1.77±0.1 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
DMSO: soluble
form 
solid
pka
14.06±0.60(Predicted)
color 
white
InChI
InChI=1S/C10H13N5O2/c1-5-6(16)2-7(17-5)15-4-14-8-9(11)12-3-13-10(8)15/h3-7,16H,2H2,1H3,(H2,11,12,13)/t5-,6+,7-/m1/s1
InChIKey
FFHPXOJTVQDVMO-DSYKOEDSSA-N
SMILES
C[C@H]1O[C@@H](N2C3C(=C(N=CN=3)N)N=C2)C[C@@H]1O
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Safety Information

WGK Germany 
3
HS Code 
29349990

MSDS

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2',5'-DIDEOXYADENOSINE Usage And Synthesis

Chemical Properties

White solid

Uses

2′,5′-Dideoxyadenosine has been used to elucidate the mechanism of diligustilide (DLG). It has also been used to inhibit adenylate cyclase (AC).

Biochem/physiol Actions

Cell-permeable adenylyl cyclase inhibitor. IC50 = 2.7 μM in detergent-dispersed rat brain preparations.

in vivo

2',5'-Dideoxyadenosine (0.1 mg/kg; IP; 15 min pre-treated) fully inhibits the diuretic, natriuretic and K+ and Cl- sparing effect of Fr EtOAc in rats[4].

Animal Model:Male Wistar rats (3-4 months old)[3]
Dosage:0.1 mg/kg
Administration:IP; 15 min pre-treated
Result:Fully inhibited the diuretic, natriuretic and K+ and Cl- sparing effect of Fr?EtOAc in rats.

2',5'-DIDEOXYADENOSINESupplier

ChemeGen(Shanghai) Biotechnology Co.,Ltd. Gold
Tel
18818260767
Email
sales@chemegen.com
Suzhou Zhixin Biotechnology Co., Ltd. Gold
Tel
0512-65118909 18100677375
Email
sales@szzxbio.com
J & K SCIENTIFIC LTD.
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18210857532; 18210857532
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jkinfo@jkchemical.com
3B Pharmachem (Wuhan) International Co.,Ltd.
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821-50328103-801 18930552037
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3bsc@sina.com
Syntechem Co.,Ltd
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Email
info@syntechem.com
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2',5'-DIDEOXYADENOSINE(6698-26-6)Related Product Information