3-Pyridylacetic acid Chemical Properties

Melting point:

144-146°C

Boiling point:

301.6±17.0 °C(Predicted)

Density 

1.245±0.06 g/cm3(Predicted)

storage temp. 

Inert atmosphere,Room Temperature

solubility 

Soluble in DMSO

form 

crystalline solid

pka

3.59±0.10(Predicted)

color 

White to off-white

InChI

InChI=1S/C7H7NO2/c9-7(10)4-6-2-1-3-8-5-6/h1-3,5H,4H2,(H,9,10)

InChIKey

WGNUNYPERJMVRM-UHFFFAOYSA-N

SMILES

C1=NC=CC=C1CC(O)=O

CAS DataBase Reference

501-81-5(CAS DataBase Reference)

EPA Substance Registry System

3-Pyridineacetic acid (501-81-5)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36/37/39-36

Hazard Note 

Irritant

HS Code 

29339900

MSDS

• Language:English Provider:2-(3-Pyridyl)acetic acid

3-Pyridylacetic acid Usage And Synthesis

Chemical Properties

Off-white to light yellow solid

Definition

ChEBI: A monocarboxylic acid that is acetic acid substituted by a (pyridin-3-yl) group. It is a metabolite of nicotine and other tobacco alkaloids.

Synthesis

(1) 2-(pyridin-3-yl)acetic acid hydrochloride (13.2 g, 75.6 mmol) was suspended in ethanol (100 mL) and an ethanol solution of 0.5 mol/L potassium hydroxide (150 mL) was slowly added. The reaction mixture was stirred until homogeneous and then filtered to remove the resulting potassium chloride precipitate. The filtrate was concentrated and dried to give 2-(pyridin-3-yl)acetic acid (10.6 g, quantitative yield).

References

[1] Patent: EP1559716, 2005, A1. Location in patent: Page/Page column 20

3-Pyridylacetic acid(501-81-5)Related Product Information

• 2-Chloro-3-cyanopyridine
• Hyaluronic acid
• Folic acid
• Acetic acid
• Ethyl 2-(Chlorosulfonyl)acetate
• Pyridine
• 3-Aminopyridine
• Trifluoroacetic acid
• Ethyl acetate
• Citric acid
• Ascoric Acid
• 4-PYRIDYLACETIC ACID 99%
• Phenylacetic acid
• Acetic anhydride
• Chloroacetic acid
• 6-Chloro-3-pyridineacetic acid, 97%
• Peroxyacetic acid
• 4-Pyridineacetic acid hydrochloride