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4-Chlorocinnamic acid

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4-Chlorocinnamic acid Basic information

Product Name:
4-Chlorocinnamic acid
Synonyms:
  • (2E)-3-(4-chlorophenyl)acrylic acid
  • 4-Chlorocinncmic Acid
  • 2-propenoic acid, 3-(4-chlorophenyl)-, (2E)-
  • PARA-CHLOROCINNAMICACID
  • 4-Chlorocinnamic acid,trans-3-(4-Chlorophenyl)propenoic acid
  • trans-4-Chlorocinnamic acid 98%
  • 4-Chlorociamic acid
  • (2E)-3-(4-Chlorophenyl)prop-2-enoic acid, (2E)-3-(4-Chlorophenyl)acrylic acid
CAS:
1615-02-7
MF:
C9H7ClO2
MW:
182.6
EINECS:
216-564-8
Product Categories:
  • Benzene series
  • Cinnamic acid
  • Aromatics Compounds
  • Acids & Esters
  • Chlorine Compounds
  • Aromatics
  • 1615-02-7
  • 11
Mol File:
1615-02-7.mol
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4-Chlorocinnamic acid Chemical Properties

Melting point:
248-250 °C(lit.)
Boiling point:
260.71°C (rough estimate)
Density 
1.2377 (rough estimate)
refractive index 
1.5426 (estimate)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
pka
4.41(at 25℃)
form 
Fine Crystalline Powder
color 
White
BRN 
1365308
InChIKey
GXLIFJYFGMHYDY-ZZXKWVIFSA-N
CAS DataBase Reference
1615-02-7(CAS DataBase Reference)
NIST Chemistry Reference
p-Chlorocinnamic acid(1615-02-7)
EPA Substance Registry System
2-Propenoic acid, 3-(4-chlorophenyl)- (1615-02-7)
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Safety Information

Hazard Codes 
Xn,Xi
Risk Statements 
22-36/37/38-20/21/22
Safety Statements 
36-28A-26-24/25
WGK Germany 
3
RTECS 
GD8490000
Hazard Note 
Irritant
HS Code 
29163990

MSDS

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4-Chlorocinnamic acid Usage And Synthesis

Chemical Properties

white to light yellow crystal powder

Uses

4-Chlorocinnamic Acid is a derivative of Cinnamic Acid (C442030) and plays an important role in the development of plants. 4-Chlorocinnamic Acid may also show potential antimicrobial, antioxidant, anti-inflammatory, and antitumoral activity.

Definition

ChEBI: 4-chlorocinnamic acid is an organochlorine compound comprising trans-cinnamic acid having a chloro substituent at the 4-position on the phenyl ring. It is functionally related to a trans-cinnamic acid.

Purification Methods

Recrystallise the acid from EtOH or aqueous EtOH (charcoal). UV has max at 275nm (EtOH). [Walling & Wolfstirn J Am Chem Soc 69 852 1947, Beilstein 9 H 596, 9 II 395, 9 III 2727, 9 IV 2033.]

4-Chlorocinnamic acid Preparation Products And Raw materials

Preparation Products

Raw materials

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