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Secretin (human)

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Secretin (human) Basic information

Product Name:
Secretin (human)
Synonyms:
  • SECRETIN, HUMAN
  • HSDGTFTSELSRLREGARLQRLLQGLV-NH3
  • HSDGTFTSELSRLREGARLQRLLQGLV-NH2
  • HIS-SER-ASP-GLY-THR-PHE-THR-SER-GLU-LEU-SER-ARG-LEU-ARG-GLU-GLY-ALA-ARG-LEU-GLN-ARG-LEU-LEU-GLN-GLY-LEU-VAL-NH2
  • HIS-SER-ASP-GLY-THR-PHE-THR-SER-GLU-LEU-SER-ARG-LEU-ARG-GLU-GLY-ALA-ARG-LEU-GLN-ARG-LEU-LEU-GLN-GLY-LEU-VAL-NH2 HUMAN
  • H-HIS-SER-ASP-GLY-THR-PHE-THR-SER-GLU-LEU-SER-ARG-LEU-ARG-GLU-GLY-ALA-ARG-LEU-GLN-ARG-LEU-LEU-GLN-GLY-LEU-VAL-NH2
  • Secretin human, ≥97% (HPLC)
  • H-HIS-SER-ASP-GLY-THR-PHE-THR-SER-GLU-LEU-SER-ARG-LEU-ARG-GLU-GLY-ALA-ARG-LEU-GLN-ARG-LEU-LEU-GLN-GLY-LEU-VAL-NH3
CAS:
108153-74-8
MF:
C130H220N44O40
MW:
3039.41
EINECS:
241-105-3
Product Categories:
  • EndocrinologyandHormones
  • Peptide
  • Gastrointestinal Peptides
  • Hormones
  • Other Protein/Peptide Hormones
  • SecretinPeptides for Cell Biology
  • Secretins
  • VIP and PACAP receptor
Mol File:
108153-74-8.mol
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Secretin (human) Chemical Properties

Density 
1.49±0.1 g/cm3(Predicted)
storage temp. 
−20°C
form 
powder
Water Solubility 
Soluble to 1 mg/ml in water
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Safety Information

WGK Germany 
3
RTECS 
VS4030000

MSDS

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Secretin (human) Usage And Synthesis

Uses

Stimulates pancreatic and gastric secretions to aid in the diagnosis of pancreatic exocrine dysfunction and the diagnosis of gastrinoma.

Uses

Secretin human has been used:

  • in the radioimmunoassay with oxyntomodulin
  • to test its effect on the enlargement and swelling of human endoderm stem cells (hEnSCs) derived cyst
  • to stimulate human induced pluripotent stem cells (iPSC)-derived biliary cells in cyclic adenosine monophosphate (cAMP) assays to test its effect on cAMP production

brand name

SecretinKabi (KabiVitrum, Sweden).

General Description

Secretin is a gastrointestinal hormone and a neuropeptide. It is synthesized from a precursor protein and shares sequence homology with other secretin family proteins like glucagon and vasoactive intestinal peptide (VIP).

Biochem/physiol Actions

Secretin regulates the secretion of gastric acid and pancreatic bicarbonates. It serves as an antidiuretic hormone in the neurohypophysial-renal axis and participates in osmoregulation. Secretin mediates its function through the G-protein coupled secretin receptors. It regulates the pH of the duodenal by modulating gastric acid secretion.

storage

Store at -20°C

Secretin (human)Supplier

3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Email
3bsc@sina.com
GL Biochem (Shanghai) Ltd
Tel
21-61263452 13641803416
Email
ymbetter@glbiochem.com
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Hunan Hui Bai Shi Biotechnology Co., Ltd.
Tel
0731-85526065 13308475853
Email
ivy@hnhbsj.com