7-CHLORO-1,3DIHYDRO-5-FLUOROPHENYL-2-NITRO-METHYLENE-2H-1,4-BENZODIAZEPINE-4-OXIDE Chemical Properties

Melting point:

240-243 °C(Solv: N,N-dimethylformamide (68-12-2); water (7732-18-5))

Boiling point:

539.7±60.0 °C(Predicted)

Density 

1.49±0.1 g/cm3(Predicted)

pka

-1.18±0.20(Predicted)

InChI

InChI=1S/C16H11ClFN3O3/c17-10-5-6-15-13(7-10)16(12-3-1-2-4-14(12)18)20(22)8-11(19-15)9-21(23)24/h1-7,9,19H,8H2

InChIKey

YFNLLWWUWXVJOM-UHFFFAOYSA-N

SMILES

N1C2=CC=C(Cl)C=C2C(C2=CC=CC=C2F)=[N+]([O-])CC1=C[N+]([O-])=O

7-CHLORO-1,3DIHYDRO-5-FLUOROPHENYL-2-NITRO-METHYLENE-2H-1,4-BENZODIAZEPINE-4-OXIDE Usage And Synthesis

Uses

7-Chloro-5-(2-fluorophenyl)-2,3-dihydro-2-(nitromethylene)-1H-1,4-benzodiazepine 4-Oxide is the synthetic precursor of Midazolam (M343000), an anesthetic, anticonvulsant, sedative and hypotic agent.

7-CHLORO-1,3DIHYDRO-5-FLUOROPHENYL-2-NITRO-METHYLENE-2H-1,4-BENZODIAZEPINE-4-OXIDE(60656-76-0)Related Product Information

• N-desalkylflurazepam
• 2-AMINOMETHYL-7-CHLORO-2,3-DIHYDRO-5-(2-FLUOROPHENYL)-1H-1,4-BENZODIAZEPINE DIMALEATE
• 8-chloro-6-(o-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid
• 5,6-Dihydro Midazolam
• 8-Chloro-6-(2-fluorophenyl)-1-methyl-6H-Imidazo[1,5-a][1,4]benzodiazepine
• 8-Chloro-1-methyl-6-phenyl-4H-Imidazo[1,5-a][1,4]benzodiazepine
• 8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine 5-Oxide
• Midazolam
• 8-CHLORO-3A,4-DIHYDRO-6-(2-FLUOROPHENYL)-1-METHYL-3H-IMIDAZO[1,5-A][1,4]BENZO-DIAZEPINE
• Midazolam EP Impurity J
• 6-Chloro-2-methyl-4-(2-fluorophenyl)quinazoline