trimethylcolchicinic acid methyl ether
trimethylcolchicinic acid methyl ether Basic information
- Product Name:
- trimethylcolchicinic acid methyl ether
- Synonyms:
-
- trimethylcolchicinic acid methyl ether
- (S)-7-Amino-6,7-dihydro-1,2,3,10-tetramethoxybenzo[a]heptalen-9(5H)-one
- Deacetylcolchicine
- Desacetylcolchicine
- (S)-N-Deacetyl Colchicine
- (7S)-7-Amino-1,2,3,10-Tetramethoxy-6,7-Dihydro-5H-Benzo[g]Heptalen-9-One
- (-)-7-Deacetylcolchicine
- (7S)-7-AMino-6,7-dihydro-1,2,3,10-tetraMethoxy-benzo[a]heptalen-9(5H)-one
- CAS:
- 3476-50-4
- MF:
- C20H23NO5
- MW:
- 357.4
- Product Categories:
-
- Amines
- Chiral Reagents
- Heterocycles
- Inhibitors
- Intermediates & Fine Chemicals
- Amines, Chiral Reagents, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
- Pharmaceuticals
- Mol File:
- 3476-50-4.mol
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trimethylcolchicinic acid methyl ether Chemical Properties
- Boiling point:
- 490.03°C (rough estimate)
- Density
- 1.2532 (rough estimate)
- refractive index
- 1.5614 (estimate)
- storage temp.
- -20°C Freezer, Under Inert Atmosphere
- solubility
- DMSO: 25mg/mL; Ethanol: 25mg/mL
- form
- A crystalline solid
- pka
- 8.62±0.40(Predicted)
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trimethylcolchicinic acid methyl ether Usage And Synthesis
Chemical Properties
Yellow Solid
Uses
An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.
Definition
ChEBI: Deacetylcolchicine is a carbotricyclic compound, an alkaloid and a member of acetamides.
trimethylcolchicinic acid methyl etherSupplier
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trimethylcolchicinic acid methyl ether(3476-50-4)Related Product Information
- GLORIOSINE
- Colchicine
- DEMECOLCINE
- COLCHICOSIDE
- COLCHICINE, [RING C, METHOXY-14C]
- DEMECOLCINE HYDROGEN BROMIDE SALT
- COLCHICINE-D6
- COLCHICINE, [RING C, METHOXY-3H]
- DEMECOLCINE-D6
- trimethylcolchicinic acid methyl ether
- DEMECOLCINE-D3
- N-TRIFLUOROACETYL-N-METHYL-DEACETYLCOLCHICINE
- N-TRIFLUOROACETYL DEACETYLCOLCHICINE
- COLCHICINE-D3
- COLCHICINE METHANETHIOSULFONATE
- N-(2-MERCAPTOETHYL) DEMECOLCINE
- TRIMETHYLCOLCHICINIC ACID
- NBD-DEMECOLCIN