Basic information Safety Supplier Related

trimethylcolchicinic acid methyl ether

Basic information Safety Supplier Related

trimethylcolchicinic acid methyl ether Basic information

Product Name:
trimethylcolchicinic acid methyl ether
Synonyms:
  • trimethylcolchicinic acid methyl ether
  • (S)-7-Amino-6,7-dihydro-1,2,3,10-tetramethoxybenzo[a]heptalen-9(5H)-one
  • Deacetylcolchicine
  • Desacetylcolchicine
  • (S)-N-Deacetyl Colchicine
  • (7S)-7-Amino-1,2,3,10-Tetramethoxy-6,7-Dihydro-5H-Benzo[g]Heptalen-9-One
  • (-)-7-Deacetylcolchicine
  • (7S)-7-AMino-6,7-dihydro-1,2,3,10-tetraMethoxy-benzo[a]heptalen-9(5H)-one
CAS:
3476-50-4
MF:
C20H23NO5
MW:
357.4
Product Categories:
  • Amines
  • Chiral Reagents
  • Heterocycles
  • Amines, Chiral Reagents, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
  • Inhibitors
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
Mol File:
3476-50-4.mol
More
Less

trimethylcolchicinic acid methyl ether Chemical Properties

Boiling point:
490.03°C (rough estimate)
Density 
1.2532 (rough estimate)
refractive index 
1.5614 (estimate)
storage temp. 
-20°C Freezer, Under Inert Atmosphere
solubility 
DMSO: 25mg/mL; Ethanol: 25mg/mL
form 
A crystalline solid
pka
8.62±0.40(Predicted)
More
Less

trimethylcolchicinic acid methyl ether Usage And Synthesis

Chemical Properties

Yellow Solid

Uses

An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.

Definition

ChEBI: Deacetylcolchicine is a carbotricyclic compound, an alkaloid and a member of acetamides.

trimethylcolchicinic acid methyl etherSupplier

J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Email
jkinfo@jkchemical.com
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Shanghai TaoSu Biochemical Technology Co., Ltd.
Tel
021-33632979
Email
info@tsbiochem.com
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Email
info@efebio.com
Shanghai SuperLan Chemcial Technique Centre
Tel
0-2022843681 15618226720
Email
chaolaichem@foxmail.com