Basic information Safety Supplier Related

amauromine

Basic information Safety Supplier Related

amauromine Basic information

Product Name:
amauromine
Synonyms:
  • amauromine
  • (5aS)-8aα,16aα-Bis(1,1-dimethyl-2-propenyl)-5aα,8,8a,13,13aα,15aβ,16,16a-octahydropyrazino[1'',2'':1,5:4'',5'':1',5']dipyrrolo[2,3-b:2',3'-b']diindole-7,15(5H,7aβH)-dione
  • Antibiotic FR-900220
  • FR-900220
  • WF-6237
  • (5aS,7aS,8aR,13aS,15aS,16aR)-8a,16a-Bis(1,1-dimethyl-2-propen-1-yl)-5a,8,8a,13,13a,15a,16,16a-octahydro-pyrazino[1'',2'':1,5
  • 4'',5'':1',5']dipyrrolo[2,3-b:2',3'-b']diindole-7,15(5H,7aH)-dione
  • 4'',5'':1',5']dipyrrolo[2,3-b:2',3'-b']diindole-7,15(5H,7aH)-dione, 8a,16a-bis(1,1-dimethyl-2-propen-1-yl)-5a,8,8a,13,13a,15a,16,16a-octahydro-, (5aS,7aS,8aR,13aS,15aS,16aR)-
CAS:
88360-87-6
MF:
C32H36N4O2
MW:
508.662
Mol File:
88360-87-6.mol
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amauromine Chemical Properties

Boiling point:
689.9±55.0 °C(Predicted)
Density 
1.28±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
form 
A solid
pka
3.26±0.60(Predicted)
color 
Brown
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Safety Information

Toxicity
LD50 intraperitoneal in mouse: > 200mg/kg
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amauromine Usage And Synthesis

Description

Amauromine is a neutral antagonist of the cannabinoid (CB) receptor CB1 that is selective for CB1 (Ki = 178 nM; Kb = 66.6 nM) over CB2, with no activity at CB2 receptors at concentrations up to 10 μM. It is also an antagonist of GPR18 (IC50 = 3.74 μM). Amauromine has vasodilatory activity.

Uses

Amauromine is a CB1 and Calcium Channel antagonist.

storage

+4°C

amauromineSupplier

Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Email
info@efebio.com
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Meng Cheng Technology (Shanghai) Co., LTD
Tel
400-820-6829
Email
sales@mitachieve.com
Energy Chemical
Tel
021-58432009 400-005-6266
Email
marketing@energy-chemical.com
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
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amauromine(88360-87-6)Related Product Information