CYCLO(-LEU-GLY)
CYCLO(-LEU-GLY) Basic information
- Product Name:
- CYCLO(-LEU-GLY)
- Synonyms:
-
- C(LEU-GLY)
- CYCLO(GLY-L-LEU)
- CYCLO(-LEU-GLY)
- CYCLO(L-LEU-GLY)
- MORPHINE TOLERANCE PEPTIDE
- MORPHIN, TOLERANCE PEPTIDE
- 2,5-Piperazinedione,3-(2-methylpropyl)-, (3S)-
- Cyclo(Gly-Leu-)
- CAS:
- 5845-67-0
- MF:
- C8H14N2O2
- MW:
- 170.21
- Mol File:
- 5845-67-0.mol
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CYCLO(-LEU-GLY) Chemical Properties
- Melting point:
- 255℃
- Boiling point:
- 442.9±38.0 °C(Predicted)
- Density
- 1.047
- storage temp.
- -15°C
- solubility
- DMSO (Sparingly), Methanol (Slightly), Water (Slightly)
- pka
- 13.22±0.40(Predicted)
- form
- Solid
- color
- White to Off-White
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CYCLO(-LEU-GLY) Usage And Synthesis
Chemical Properties
White powder
Uses
Cyclo(Leu-Gly) is an antimicrobial compound produced by Latobacillus plantarum.
in vivo
Cyclo(glycyl-L-leucyl) (8 mg/kg; s.c.) given 24h after apomorphine (APO) attenuates the DA receptor supersensitivity caused by acute high dose APO (5 mg/kg; s.c.)[1].
| Animal Model: | Male Swiss-Webster mice, 20-25g[1] |
| Dosage: | 8 mg/kg |
| Administration: | SC; single dose given 24h after apomorphine (APO) |
| Result: | Attenuated the DA receptor supersensitivity caused by acute high dose APO (5 mg/kg; s.c.). |
IC 50
Dopamine Receptor
CYCLO(-LEU-GLY)Supplier
ForeChem (Nantong) Technology Co.,Ltd.
- Tel
- 513-85982855 18921614129
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GL Biochem (Shanghai) Ltd
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- 21-61263452 13641803416
- ymbetter@glbiochem.com
Chemsky（shanghai）International Co.,Ltd.
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- 021-50135380
- shchemsky@sina.com
Tianjin Derchemist Science & Technology Co., Ltd.
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- 22-58627059 13920586291
- zdcomcon@126.com
Dtchem Laboratories,（Gan Su）Co.,Ltd.
- Tel
- 18993966060
- sales@techbiochem.com