ceanothic acid
ceanothic acid Basic information
- Product Name:
- ceanothic acid
- Synonyms:
-
- ceanothic acid
- 2α-Carboxy-3β-hydroxy-A(1)-nor-5α-lupan-20(29)-en-28-oic acid
- Emmolic acid
- Ceathic acid
- Americana acid
- 3'H-Cyclopenta[3,4]-18-norandrost-3-ene-3',13-dicarboxylicacid, tetrahydro-4'-hydroxy-4,5',5',9-tetramethyl-15-(1-methylethenyl)-, (3b,3'b,4a,4'a,5b,8a,9b,10a,13a,14b,15b)-
- 3'H-Cyclopenta[3,4]-18-norandrost-3-ene-3',13-dicarboxylic acid, tetrahydro-4'-hydroxy-4,5',5',9-tetramethyl-15-(1-methylethenyl)-, (3β,3'β,4α,4'α,5β,8α,9β,10α,13α,14β,15β)-
- (1R,2S,3aR,5aR,5bR,7aS,10R,10aR,10bR,12aR,12bR)-2-Hydroxy-10-isopropenyl-3,3,5a,5b,12b-pentamethyloctadecahydrodicyclopenta[a,i]phenanthrene-1,7a(1H)-dicarboxylicaci
- CAS:
- 21302-79-4
- MF:
- C30H46O5
- MW:
- 486.68
- Mol File:
- 21302-79-4.mol
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ceanothic acid Chemical Properties
- Melting point:
- 356-357°
- alpha
- D +38° (c = 1.20 in ethanol)
- Boiling point:
- 609.0±55.0 °C(Predicted)
- Density
- 1.149±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- Powder
- pka
- 4.46±0.70(Predicted)
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ceanothic acid Usage And Synthesis
Uses
Ceanothic acid is a natural product extracted from the jujube plant Z. cambodiana Pierre. The jujube plant Z. cambodiana Pierre is widely distributed in northeastern Thailand and is a traditional medicine used to fight infection.
Preparation
The dried root bark of the plant was degreased with hexane, followed by extraction with ethyl acetate and methanol at 50 °C for 50 h. This solvent was used to elute, and compounds 1 to 9 were isolated. 9 was the Ceanothic acid.
Biological Activity
Ceanothic acid (Emmolic acid) is a homologue of betulinic acid. It inhibited OVCAR-3, HeLa and FS-5 cells with cell viability of 68%, 65% and 81%, respectively.
ceanothic acidSupplier
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