Methyltriphenylphosphonium bromide Chemical Properties

Melting point:

230-234 °C (lit.)

vapor pressure 

0.0000002 hPa

Flash point:

>240°C

storage temp. 

Inert atmosphere,Room Temperature

solubility 

H₂O: 0.1 g/mL, clear

form 

Powder

color 

White

PH

6.0-6.5 (400g/l, H2O, 20℃)

Water Solubility 

400 g/L (25 ºC)

Sensitive 

Hygroscopic

BRN 

3599467

InChIKey

LSEFCHWGJNHZNT-UHFFFAOYSA-M

LogP

-1.18

CAS DataBase Reference

1779-49-3(CAS DataBase Reference)

NIST Chemistry Reference

Methyltriphenylphosphonium bromide(1779-49-3)

EPA Substance Registry System

Phosphonium, methyltriphenyl-, bromide (1779-49-3)

Safety Information

Hazard Codes 

Xn,Xi

Risk Statements 

20/21/22-36/37/38

Safety Statements 

36/37-36-26

RIDADR 

UN 1390 4.3/PG 2

WGK Germany 

3

Autoignition Temperature

410 °C

TSCA 

T

HazardClass 

6.1

PackingGroup 

III

HS Code 

29310095

Toxicity

LD50 orally in Rabbit: 118 mg/kg

MSDS

• Language:English Provider:Methyltriphenylphosphonium bromide
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Methyltriphenylphosphonium bromide Usage And Synthesis

Chemical Properties

white powder

Uses

Methyltriphenylphosphonium bromide is used for methylenation through the Wittig reaction. It is utilized in the synthesis of an enyne and 9-isopropenyl -phenanthrene by using sodium amide as reagent. It is a lipophilic molecule and used to deliver molecules to specific cell components. Further, it acts as an antineoplastic agent.

Uses

Methyltriphenylphosphonium Bromide is a lipophilic molecule with a cation allowing for it to be used to deliver molecules to specific cell components. Also considered an antineoplastic agent.

Uses

PTC catalyst

General Description

Methyltriphenylphosphoniumbromide is an organophosphorus compound, with potential use as a precursor and a solvent in organic synthesis.

Mettler-Toledo calibration substance ME 30130598, methyltriphenylphosphoniumbromide is ideal for use in the regular calibration of Mettler-Toledo melting point instrument. Its value is a mean of 6 to 12 iterations with a Mettler-Toledo MP70 Excellence instrument that is calibrated against primary standards. The melting point is validated by Capillary method according to European Pharmacopeia (2.2.14.)

Purification Methods

If the solid is sticky, wash it with *C6H6 and dry it in a vacuum over P2O5. [Marvel & Gall J Org Chem 24 1494 1959, Chem Ber 87 1318 1954, Milas & Priesing J Am Chem Soc 79 6295 1957, Wittig & Sch.llkopf Org Synth 40 66 1960.] The iodide, on recrystallisation from H2O, has m 187.5-188.5o [Mann et al. J Chem Soc 1130 1953, Wittig & Geissler Justus Liebigs Ann Chem 580 44 1953]. [Beilstein 16 IV 981.]

Methyltriphenylphosphonium bromide(1779-49-3)Related Product Information

• Allyl bromide
• Rocuronium bromide
• Bensulfuron methyl
• Tetraphenylphosphonium bromide
• Thiophanate-methyl
• Sodium bromate
• Dichloromethylphenylsilane
• Ethidium bromide
• Boron tribromide
• Triphenylphosphine hydrobromide
• Triphenylphosphine
• Methyl salicylate
• Triphenylphosphine oxide
• Phosphorus tribromide
• Methyltriphenylphosphonium iodide
• Methyl(triphenyl)phosphonium chloride
• Methyl trioctyl ammonium chloride
• potassium methyltrifluoroborate