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2,4-Dihydroxy-6-methoxy-3-methylacetophenone

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2,4-Dihydroxy-6-methoxy-3-methylacetophenone Basic information

Product Name:
2,4-Dihydroxy-6-methoxy-3-methylacetophenone
Synonyms:
  • Ebracteolata cpd B
  • 2,4-Dihydroxy-6-methoxy-3-methylacetophenone
  • Ethanone, 1-(2,4-dihydroxy-6-methoxy-3-methylphenyl)-
  • 1-(2,4-Dihydroxy-6-methoxy-3-methylphenyl)ethanone
CAS:
83459-37-4
MF:
C10H12O4
MW:
196.2
Mol File:
83459-37-4.mol
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2,4-Dihydroxy-6-methoxy-3-methylacetophenone Chemical Properties

Melting point:
224℃
Boiling point:
355.5±22.0 °C(Predicted)
Density 
1.240±0.06 g/cm3(Predicted)
pka
7.95±0.28(Predicted)
InChI
InChI=1S/C10H12O4/c1-5-7(12)4-8(14-3)9(6(2)11)10(5)13/h4,12-13H,1-3H3
InChIKey
RFKMWWMZUHXFBA-UHFFFAOYSA-N
SMILES
C(=O)(C1=C(OC)C=C(O)C(C)=C1O)C
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2,4-Dihydroxy-6-methoxy-3-methylacetophenone Usage And Synthesis

Uses

Ebracteolata cpd B is a natural phenol compound found in Euphorbia ebracteolata[1].

Preparation

Preparation by reduction of 3-formyl-2,4-dihydroxy- 6-methoxyacetophenone with hydrochloric acid and amalgamated zinc in gently heated aqueous methanol (64%).

References

[1] Zhuang G, et al. Study on HPLC chromatograms of different processed Euphorbia ebracteolata products and content change of three chemical components. Zhongguo Zhong Yao Za Zhi. 2013 May;38(10):1526-30. Chinese. PMID:23947130

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