Prudomestin Chemical Properties

Melting point:

209-210 °C

Boiling point:

568.9±50.0 °C(Predicted)

Density 

1.507±0.06 g/cm3(Predicted)

storage temp. 

Store at -20°C

solubility 

Soluble in DMSO

form 

Solid

pka

6.65±0.40(Predicted)

color 

Light yellow to yellow

Prudomestin Usage And Synthesis

Uses

Prudomestin, isolated from the heartwood of Prunus domestica, shows potent xanthine oxidase (XO) inhibitory activity (IC50≈6?μM)[1][2].

Definition

ChEBI: Prudomestin is a hydroxyflavan.

References

[1] Nooreen Z, et al. Characterization and evaluation of bioactive polyphenolic constituents from Zanthoxylum armatum DC., a traditionally used plant. Biomed Pharmacother. 2017 May;89:366-375. DOI:10.1016/j.biopha.2017.02.040
[2] Ranjana, et al. Standardization and xanthine oxidase inhibitory potential of Zanthoxylum armatum fruits. J Ethnopharmacol. 2019 Feb 10;230:1-8. DOI:10.1016/j.jep.2018.10.018

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