2'-O-Methylhelichrysetin Chemical Properties

Melting point:

192-193 °C

Boiling point:

556.0±50.0 °C(Predicted)

Density 

1.279±0.06 g/cm3(Predicted)

storage temp. 

2-8°C

solubility 

DMSO: 2mg/mL, clear

form 

powder

pka

7.18±0.25(Predicted)

color 

white to beige

2'-O-Methylhelichrysetin Usage And Synthesis

Definition

ChEBI: 4,4'-Dihydroxy-2',6'-dimethoxychalcone is a member of phenols.

Biological Activity

CH625 is a potent and selective competitive inhibitor of CYP4X1 th at decreases tumor burden, increases survival in glioma intracranial and subcutaneous model in rats. CH625 normalizes tumor vasculature in the C6 and GL261 gliomas through tumor-associated macrophages (TAMs) reprograming and inhibition of VEGF and TGF-β production.

2'-O-Methylhelichrysetin(123316-64-3)Related Product Information

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