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2-Chlorothiophene

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2-Chlorothiophene Basic information

Product Name:
2-Chlorothiophene
Synonyms:
  • ChloroThiophene
  • 2-Chlorothiophene,97%
  • 2-Chlorothiphene
  • 2 - chloride thiophene
  • 2-Chlorothiophene, 98+%
  • 2-Chlorothiophene, 98+% 25ML
  • 2-CHLOROTHIOPHENE
  • 2-THIENYL CHLORIDE
CAS:
96-43-5
MF:
C4H3ClS
MW:
118.58
EINECS:
202-505-3
Product Categories:
  • 12
  • Thiophene&Benzothiophene
  • Thiophenes
  • CHIRAL CHEMICALS
  • Heterocycle-oher series
Mol File:
96-43-5.mol
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2-Chlorothiophene Chemical Properties

Melting point:
-71.9 °C
Boiling point:
127-129 °C (lit.)
Density 
1.286 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.547(lit.)
Flash point:
73 °F
storage temp. 
2-8°C
solubility 
soluble in Chloroform
form 
Liquid
color 
Clear colorless to light brown
Specific Gravity
1.286
Water Solubility 
INSOLUBLE
BRN 
104652
Stability:
Volatile
InChIKey
GSFNQBFZFXUTBN-UHFFFAOYSA-N
CAS DataBase Reference
96-43-5(CAS DataBase Reference)
NIST Chemistry Reference
Thiophene, 2-chloro-(96-43-5)
EPA Substance Registry System
Thiophene, 2-chloro- (96-43-5)
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Safety Information

Hazard Codes 
Xi,F,T
Risk Statements 
10-36/37/38-23/24/25-37
Safety Statements 
16-26-36-45-38-36/37/39-28B-7/9
RIDADR 
UN 1993 3/PG 3
WGK Germany 
3
RTECS 
XM8575000
Hazard Note 
Irritant
TSCA 
T
HazardClass 
3
PackingGroup 
II
HS Code 
29349990

MSDS

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2-Chlorothiophene Usage And Synthesis

Chemical Properties

Colorless to light yellow liquid

Uses

2-Chlorothiophene was used in the preparation of 5-phenylthiophene derivative.

Application

2-Chlorothiophene is a heterocyclic compound that belongs to the group of organic compounds called thiophenes. It is an effective analgesic and anti-inflammatory drug that has been used in the treatment of inflammatory bowel disease. 2-Chlorothiophene is used as a reagent in chemical synthesis, especially the preparation of pharmaceutical preparations. This compound can be prepared by photoelectron or hydrochloric acid. The suzuki coupling reaction with pyrimidine compounds is another method for synthesizing this compound.

General Description

The photodissociation dynamics of 2-chlorothiophene was studied using resonance enhanced multiphoton ionization (REMPI) time-of-flight (TOF) technique.

Purification Methods

Purify it by fractional distillation at atmospheric pressure or by gas chromatography. [Conde et al. Synthesis 412 1976, Beilstein 17/1 V 303.]

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